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HXK2 protein (Arabidopsis thaliana) - STRING interaction network
"HXK2" - Hexokinase-2 in Arabidopsis thaliana
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Predicted Interactions
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HXK2Hexokinase-2; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells; Belongs to the hexokinase family (502 aa)    
Predicted Functional Partners:
PGM2
Phosphoglucomutase/phosphomannomutase family protein; Encodes a cytosolic phosphoglucomutase (PGM). Two Arabidopsis PGM proteins (AT1G70730/PGM2 and AT1G23190/PGM3) have high sequence similarities and redundant functions. Mature plants possessing a single cPGM allele had a major reduction in cPGM activity. Whereas pgm2 and pgm3 single mutants are undistinguishable from the wild type, loss of both PGM2 and PGM3 severely impairs male and female gametophyte development (662 aa)
     
 
  0.976
AT5G42740
Glucose-6-phosphate isomerase, cytosolic; Sugar isomerase (SIS) family protein; Its function is described as glucose-6-phosphate isomerase activity; Involved in defense response to fungus, incompatible interaction, response to cadmium ion, gluconeogenesis, glycolysis; Located in cellular_component unknown; Expressed in 24 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Phosphoglucose isomerase, conserved site (InterPro-IPR018189), Phosphoglucose isomerase (PGI) (InterPro-IPR001672); BEST Arabidopsis thaliana protein match is- phosphoglucose [...] (560 aa)
     
 
  0.963
PFK2
ATP-dependent 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade "X" sub-subfamily (444 aa)
     
 
  0.962
PFK5
ATP-dependent 6-phosphofructokinase 5, chloroplastic; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade "X" sub-subfamily (537 aa)
     
 
  0.959
AT3G29320
Glycosyl transferase, family 35; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). May be not required for the degradation of starch, but the phosphorolysis of starch may play an important role in water stress tolerance (962 aa)
     
  0.957
AT5G08570
Pyruvate kinase family protein; Its function is described as pyruvate kinase activity, potassium ion binding, magnesium ion binding, catalytic activity; Involved in glycolysis; Located in cellular_component unknown; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Pyruvate kinase, C-terminal-like (InterPro-IPR015795), Pyruvate kinase, active site (InterPro-IPR018209), Pyruvate kinase, beta-barrel-like (InterPro-IPR011037), Pyruvate kinase, alpha/beta (InterPro-IPR015794), Pyruvate/Phosphoenolpyruvate kinase, catalytic core (I [...] (510 aa)
     
  0.957
PHS2
Alpha-glucan phosphorylase 2, cytosolic; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) (841 aa)
     
  0.957
GFAT
Glutamine-fructose-6-phosphate transaminase (isomerizing)s;sugar binding;transaminases; Its function is described as sugar binding, transaminase activity, glutamine-fructose-6-phosphate transaminase (isomerizing) activity; Involved in carbohydrate biosynthetic process, carbohydrate metabolic process, metabolic process; Located in cytoplasm; Expressed in 20 plant structures; Expressed during 12 growth stages; Contains the following InterPro domains- Glutamine amidotransferase, class-II (InterPro-IPR000583), Sugar isomerase (SIS) (InterPro-IPR001347), Glucosamine-fructose-6-phosphate ami [...] (677 aa)
     
 
  0.956
GNA1
Glucosamine 6-phosphate N-acetyltransferase; Acetyltransferase involved in UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis. UDP-GlcNAc is an essential metabolite that serves as an initial sugar donor for N-glycan synthesis and thus plays an important role in protein and lipid glycosylation (149 aa)
       
  0.955
AT5G63680
Pyruvate kinase family protein; Its function is described as pyruvate kinase activity, potassium ion binding, magnesium ion binding, catalytic activity; Involved in response to cadmium ion, glycolysis; Located in plasma membrane; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Pyruvate kinase, C-terminal-like (InterPro-IPR015795), Pyruvate kinase, active site (InterPro-IPR018209), Pyruvate kinase, beta-barrel-like (InterPro-IPR011037), Pyruvate kinase, alpha/beta (InterPro-IPR015794), Pyruvate/Phosphoenolpyruvate kinase, cat [...] (510 aa)
     
  0.952
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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