STRINGSTRING
PFK5 protein (Arabidopsis thaliana) - STRING interaction network
"PFK5" - ATP-dependent 6-phosphofructokinase 5, chloroplastic in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PFK5ATP-dependent 6-phosphofructokinase 5, chloroplastic; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade "X" sub-subfamily (537 aa)    
Predicted Functional Partners:
AT5G42740
Glucose-6-phosphate isomerase, cytosolic; Sugar isomerase (SIS) family protein; Its function is described as glucose-6-phosphate isomerase activity; Involved in defense response to fungus, incompatible interaction, response to cadmium ion, gluconeogenesis, glycolysis; Located in cellular_component unknown; Expressed in 24 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Phosphoglucose isomerase, conserved site (InterPro-IPR018189), Phosphoglucose isomerase (PGI) (InterPro-IPR001672); BEST Arabidopsis thaliana protein match is- phosphoglucose [...] (560 aa)
   
  0.994
PHS2
Alpha-glucan phosphorylase 2, cytosolic; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) (841 aa)
   
  0.985
AT3G29320
Glycosyl transferase, family 35; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). May be not required for the degradation of starch, but the phosphorolysis of starch may play an important role in water stress tolerance (962 aa)
   
  0.985
AT3G52990
Pyruvate kinase family protein; Its function is described as pyruvate kinase activity, potassium ion binding, magnesium ion binding, catalytic activity; Involved in response to cadmium ion, glycolysis; Located in membrane; Expressed in guard cell, cultured cell, leaf; Expressed during seedling growth; Contains the following InterPro domains- Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro-IPR015813), Pyruvate kinase, alpha/beta (InterPro-IPR015794), Pyruvate kinase, beta-barrel-like (InterPro-IPR011037), Pyruvate kinase (InterPro-IPR001697), Pyruvate kinase, C-terminal-li [...] (527 aa)
   
  0.981
PGI1
Glucose-6-phosphate isomerase 1, chloroplastic; The PGI1 gene encodes the plastid phospho-glucose (Glc) isomerase. While pgi1-1 mutant has a deficiency in leaf starch synthesis, it accumulates starch in root cap cells. Flowering time of the pgi1-1 mutant is significantly delayed under short-day conditions (613 aa)
   
  0.979
PGM3
Phosphoglucomutase/phosphomannomutase family protein; Encodes a cytosolic phosphoglucomutase (PGM). Two Arabidopsis PGM proteins (AT1G70730/PGM2 and AT1G23190/PGM3) have high sequence similarities and redundant functions. Mature plants possessing a single cPGM allele had a major reduction in cPGM activity. Whereas pgm2 and pgm3 single mutants are undistinguishable from the wild type, loss of both PGM2 and PGM3 severely impairs male and female gametophyte development (583 aa)
   
  0.976
PGM2
Phosphoglucomutase/phosphomannomutase family protein; Encodes a cytosolic phosphoglucomutase (PGM). Two Arabidopsis PGM proteins (AT1G70730/PGM2 and AT1G23190/PGM3) have high sequence similarities and redundant functions. Mature plants possessing a single cPGM allele had a major reduction in cPGM activity. Whereas pgm2 and pgm3 single mutants are undistinguishable from the wild type, loss of both PGM2 and PGM3 severely impairs male and female gametophyte development (662 aa)
   
  0.974
HXK1
Hexokinase-1; Fructose and glucose phosphorylating enzyme. May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol. Acts as sugar sensor which may regulate sugar-dependent gene repression or activation. Mediates the effects of sugar on plant growth and development independently of its catalytic activity or the sugar metabolism. May regulate the execution of program cell death in plant cells; Belongs to the hexokinase family (496 aa)
     
 
  0.973
PGMP
Phosphoglucomutase, chloroplastic; Encodes a plastid isoform of the enzyme phosphoglucomutase involved in controlling photosynthetic carbon flow. Effective petiole movement against the direction of the gravity requires functional PGM activity that is required for full development of amyloplasts (623 aa)
   
  0.973
AT5G63680
Pyruvate kinase family protein; Its function is described as pyruvate kinase activity, potassium ion binding, magnesium ion binding, catalytic activity; Involved in response to cadmium ion, glycolysis; Located in plasma membrane; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Pyruvate kinase, C-terminal-like (InterPro-IPR015795), Pyruvate kinase, active site (InterPro-IPR018209), Pyruvate kinase, beta-barrel-like (InterPro-IPR011037), Pyruvate kinase, alpha/beta (InterPro-IPR015794), Pyruvate/Phosphoenolpyruvate kinase, cat [...] (510 aa)
   
  0.967
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]