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CDPMEK protein (Arabidopsis thaliana) - STRING interaction network
"CDPMEK" - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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CDPMEK4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D- erythritol. Is essential for chloroplast development (383 aa)    
Predicted Functional Partners:
ISPD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP). Is essential for chloroplast development and required for pigments and gibberellins biosynthesis (302 aa)
 
 
  0.999
ISPF
Isoprenoid F; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 4-diphosphocytidyl-2C- methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4- cyclodiphosphate and CMP. Also converts 4-diphosphocytidyl-2C- methyl-D-erythritol into 2C-methyl-D-erythritol 3,4-cyclophosphate and CMP. Is essential for chloroplast development (231 aa)
 
 
  0.998
DXR
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP). Required for chloroplast development (497 aa)
   
   
  0.988
HDS
4-hydroxy-3-methylbut-2-enyl diphosphate synthase; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Is essential for chloroplast development and required for the salicylic acid (SA)-mediated disease resistance to biotrophic pathogens (741 aa)
   
   
  0.983
CLA1
CLOROPLASTOS ALTERADOS 1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). Is a limiting enzyme for plastidic isoprenoid biosynthesis and essential for chloroplast development (717 aa)
   
   
  0.966
HDR
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is essential for chloroplast development (466 aa)
 
   
  0.960
GPS1
Geranyl diphosphate synthase 1; May be involved in the supply of solanesyl diphosphate for ubiquinone-9 biosynthesis in mitochondria. Synthesizes C25 to C45 medium / long-chain products depending on the type of substrate available. Can use geranyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as substrates, but not dimethylallyl diphosphate (422 aa)
   
   
  0.877
MK
Mevalonate kinase (378 aa)
           
  0.863
HMGS
HYDROXYMETHYLGLUTARYL-COA SYNTHASE; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation (461 aa)
           
  0.863
AT1G31910
Phosphomevalonate kinase (505 aa)
           
  0.862
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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