STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
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CYP710A1Cytochrome P450, family 710, subfamily A, polypeptide 1; Encodes a protein with C22-sterol desaturase activity. The enzyme was shown to catalyze in the presence of NADPH the conversion of &beta;-sitosterol to stigmasterol, but not that of 24-<i>epi</i>-campesterol to brassicasterol (unlike CYP710A2); Belongs to the cytochrome P450 family (495 aa)    
Predicted Functional Partners:
DWF1
Cell elongation protein / DWARF1 / DIMINUTO (DIM); Plays a critical role in the general process of plant cell elongation. Involved in the synthesis of campesterol, an early precursor of brassinolide. Required for the conversion of 24-methylenecholesterol to campesterol and for the conversion of isofucosterol to sitosterol. Necessary for both the isomerization and reduction of 24-methylenecholesterol. Regulate indirectly phytochrome-mediated light responses through the modulation of brassinosteroid biosynthesis
     
 0.944
SMT2
24-methylenesterol C-methyltransferase 2; Encodes a sterol-C24-methyltransferases involved in sterol biosynthesis. Mutants display altered sterol composition, serrated petals and sepals and altered cotyledon vascular patterning as well as ectopic endoreduplication. This suggests that suppression of endoreduplication is important for petal morphogenesis and that normal sterol composition is required for this suppression
    
 
 0.861
AT1G53060
Lectin-like protein At1g53060; Legume lectin family protein; Its function is described as carbohydrate binding, binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Legume lectin, beta chain (InterPro:IPR001220), Concanavalin A-like lectin/glucanase, subgroup (InterPro:IPR013320), Concanavalin A-like lectin/glucanase (InterPro:IPR008985), Lectin (InterPro:IPR016363); BEST Arabidopsis thaliana protein match is: Legume lectin family protein (TAI [...]
    
 
 0.624
AT1G53070
Lectin-like protein At1g53070; Legume lectin family protein; Its function is described as carbohydrate binding, binding; Involved in response to karrikin; Located in cell wall, plant-type cell wall; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Legume lectin, beta chain (InterPro:IPR001220), Concanavalin A-like lectin/glucanase, subgroup (InterPro:IPR013320), Concanavalin A-like lectin/glucanase (InterPro:IPR008985), Lectin (InterPro:IPR016363); BEST Arabidopsis thaliana protein match is: Legume lectin family protein (TAIR [...]
    
 
 0.624
AT1G53080
Lectin-like protein At1g53080; Legume lectin family protein; Its function is described as carbohydrate binding, binding; Involved in biological_process unknown; Located in plant-type cell wall; Expressed in stem; Contains the following InterPro domains: Legume lectin, beta chain (InterPro:IPR001220), Concanavalin A-like lectin/glucanase, subgroup (InterPro:IPR013320), Concanavalin A-like lectin/glucanase (InterPro:IPR008985), Lectin (InterPro:IPR016363); BEST Arabidopsis thaliana protein match is: Legume lectin family protein (TAIR:AT3G16530.1); Has 2015 Blast hits to 1995 proteins in [...]
    
 
 0.624
FMO1
Probable flavin-containing monooxygenase 1; FMO1 is required for full expression of TIR-NB-LRR-conditioned resistance to avirulent pathogens and for basal resistance to invasive virulent pathogens. Functions in an EDS1-regulated but SA-independent mechanism that promotes resistance and cell death at pathogen infection sites
   
 
 0.608
SNG1
Serine carboxypeptidase-like 8; Involved in plants secondary metabolism. Functions as acyltransferase to form the sinapate ester sinapoylmalate. Also capable of catalyzing the formation of 1,2-bis-O-sinapoyl beta-D- glucoside; Belongs to the peptidase S10 family
    
 
 0.595
HMG1
Encodes a 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in melavonate biosynthesis and performs the first committed step in isoprenoid biosynthesis. Expression is activated in dark in leaf tissue but not controlled by light in the root (confine
   
  
 0.590
HMGS
Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation
  
 
 0.586
CB5LP
Cytochrome B5-like protein; Member of Cytochromes b5
   
 
 0.581
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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