STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT2G37660NAD(P)-binding Rossmann-fold superfamily protein; Its function is described as copper ion binding; Involved in defense response to bacterium; Located in thylakoid, apoplast, chloroplast stroma, chloroplast; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT5G02240.1); Has 2691 Blast hits to 2647 proteins in 745 specie [...] (325 aa)    
Predicted Functional Partners:
CI51
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)
   
 
 0.882
AT4G17560
50S ribosomal protein L19-1, chloroplastic; Located at the 30S-50S ribosomal subunit interface and binds directly to 23S ribosomal RNA
   
    0.880
CHLI1
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP- dependent chelation step. Possesses high affinity for ATP and may play a major role in chlorophyll biosynthesis. Does not bind abscisic acid (ABA), but is a positive regulator of ABA signaling
   
  
 0.880
AT5G47190
50S ribosomal protein L19-2, chloroplastic; Located at the 30S-50S ribosomal subunit interface and binds directly to 23S ribosomal RNA
   
    0.880
AT4G02530
Thylakoid lumenal 16.5 kDa protein, chloroplastic; Chloroplast thylakoid lumen protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in 6 components; Expressed in 22 plant structures; Expressed during 13 growth stages; Has 54 Blast hits to 54 proteins in 21 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 54; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink)
   
    0.876
PSRP2
RNA-binding (RRM/RBD/RNP motifs) family protein; Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus. May have a role in the recruitment of stored chloroplast mRNAs for active protein synthesis (By similarity). Bind single strand DNA (ssDNA) and RNA in vitro. Exhibits RNA chaperone activity. Regulates negatively resistance responses to abiotic stresses during seed ger [...]
   
    0.872
AT3G08740
Elongation factor P (EF-P) family protein; Its function is described as translation elongation factor activity; Involved in translational elongation; Located in chloroplast, chloroplast stroma; Expressed in 24 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains: Translation elongation factor P (InterPro:IPR011768), Translation elongation factor P/YeiP, conserved site (InterPro:IPR013852), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Translation elongation factor, KOW-like (InterPro:IPR013185), Translation protein SH3-like, subgroup (Inter [...]
   
    0.866
emb1473
50S ribosomal protein L13, chloroplastic; Embryo defective 1473 (emb1473); Its function is described as structural constituent of ribosome; Involved in translation, embryo development ending in seed dormancy; Located in thylakoid, ribosome, chloroplast, chloroplast stroma; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Ribosomal protein L13, bacterial-type (InterPro:IPR005823), Ribosomal protein L13 (InterPro:IPR005822); BEST Arabidopsis thaliana protein match is: Ribosomal protein L13 family protein (TAIR:AT3G01790.2); Has [...]
  
    0.865
PSRP3/1
30S ribosomal protein 3-1, chloroplastic; Probably a ribosomal protein or a ribosome-associated protein; Belongs to the chloroplast-specific ribosomal protein cS23 family
   
    0.861
EMB3143
YCF54; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in thylakoid, chloroplast; Expressed in 22 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains: Protein of unknown function DUF2488 (InterPro:IPR019616); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink)
   
    0.858
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (13%) [HD]