STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
COBL10COBRA-like protein 10 precursor (COBL10); Contains the following InterPro domains: Glycosyl-phosphatidyl inositol-anchored, plant (InterPro:IPR006918); BEST Arabidopsis thaliana protein match is: COBRA-like protein 11 precursor (TAIR:AT4G27110.1); Has 377 Blast hits to 368 proteins in 29 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 377; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink) (672 aa)    
Predicted Functional Partners:
AT5G42680
Protein of unknown function, DUF617; Its function is described as molecular_function unknown; Involved in biological_process unknown; Expressed in 18 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains: Protein of unknown function DUF617, plant (InterPro:IPR006460); BEST Arabidopsis thaliana protein match is: Protein of unknown function, DUF617 (TAIR:AT4G39610.1)
      
 0.764
AT5G14850
Alg9-like mannosyltransferase family; Its function is described as mannosyltransferase activity, transferase activity, transferring glycosyl groups; Involved in GPI anchor biosynthetic process, GPI anchor metabolic process; Located in endoplasmic reticulum membrane, intrinsic to endoplasmic reticulum membrane; Expressed in 22 plant structures; Expressed during 12 growth stages; Contains the following InterPro domains: Alg9-like mannosyltransferase (InterPro:IPR005599); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Pl [...]
      
 0.699
SETH1
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis (Probable). Required for pollen germination and pollen tube growth; Belongs to the PIGC family
      
 0.664
CHX23
Cation/H(+) antiporter 23, chloroplastic; Operates as a K(+)/H(+) antiporter or Na(+)/H(+) antiporter of the chloroplast envelope that functions in pH homeostasis and chloroplast development. Monovalent cation transporter with a preference for Cs(+), K(+) and Rb(+) relative to Na(+) or Li(+). Required for pollen tube guidance, but not for normal pollen development. May also be involved in the development or function of the female gametophyte
   
  
 0.660
POD1
Protein POLLEN DEFECTIVE IN GUIDANCE 1; Probable component of the calreticulin 3 (CRT3) complex, acting probably as a co-chaperone involved in protein retention in the endoplasmic reticulum lumen. Required for micropylar pollen tube guidance. Plays an essential role in cell plate orientation or positioning in early embryo patterning
      
 0.612
P58IPK
DnaJ protein P58IPK homolog; Plays an important positive role in viral symptom development and is required for viral multiplication and pathogenesis
      
 0.612
CHX21
Cation/H(+) antiporter 21; Operates as a Na(+)/H(+) antiporter that plays a role in regulation of xylem Na(+) concentration and, consequently, Na(+) accumulation in the leaf. Required for pollen tube guidance, but not for normal pollen development. May also be involved in the development or function of the female gametophyte; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily
      
 0.579
GSTU26
Glutathione S-transferase tau 26; In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB). May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides; Belongs to the GST superfamily. Tau family
      
 0.567
SETH2
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis (Probable). Required for pollen germination and pollen tube growth; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily
      
 0.566
RALFL15
Protein RALF-like 15; Member of a diversely expressed predicted peptide family showing sequence similarity to tobacco Rapid Alkalinization Factor (RALF), and is believed to play an essential role in the physiology of Arabidopsis. Consists of a single exon and is characterized by a conserved C-terminal motif and N-terminal signal peptide. This gene is contained within a highly AT-rich repetitive sequence region
   
  
 0.554
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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