STRING protein interaction network
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
AT3G22104BTB/POZ domain-containing protein At3g22104; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (506 aa)    
Predicted Functional Partners:
Pentatricopeptide repeat-containing protein At4g14050, mitochondrial; Involved in C-to-U editing of mitochondrial RNA. Required specifically for editing the mitochondrial NAD4, MT- CYB/COB and RPL16 transcripts
Probably inactive leucine-rich repeat receptor-like protein kinase At5g48380; Encodes a BAK1-interacting receptor-like kinase named BIR1. Negatively regulates multiple plant resistance signaling pathways, one of which is the SOBIR1(AT2G31880)-dependent pathway
Tetratricopeptide repeat (TPR)-like superfamily protein; Contains the following InterPro domains: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G21065.1); Has 36841 Blast hits to 13999 proteins in 256 species: Archae - 0; Bacteria - 8; Metazoa - 78; Fungi - 94; Plants - 36058; Viruses - 0; Other Eukaryotes - 603 (source: NCBI BLink); Belongs to the PPR family. PCMP-H subfamily
RNA-binding (RRM/RBD/RNP motifs) family protein; Its function is described as nucleic acid binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: RNA recognition motif, RNP-1 (InterPro:IPR000504); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT4G02485.1); Has 662 Blast hits to 662 proteins in 169 species: Archae - 0; Bacteria - 66; Metazoa - 255; Fungi - 80; Plants - 14 [...]
Nodulin MtN21 /EamA-like transporter family protein; Its function is described as molecular_function unknown; Located in endomembrane system, membrane; Expressed in root; Contains the following InterPro domains: Protein of unknown function DUF6, transmembrane (InterPro:IPR000620); BEST Arabidopsis thaliana protein match is: Walls Are Thin 1 (TAIR:AT1G75500.2); Has 4958 Blast hits to 4938 proteins in 907 species: Archae - 35; Bacteria - 2613; Metazoa - 8; Fungi - 3; Plants - 1244; Viruses - 0; Other Eukaryotes - 1055 (source: NCBI BLink); Belongs to the drug/metabolite transporter (DMT) [...]
65-kDa microtubule-associated protein 5; Microtubule-associated protein that bundle and stabilize adjacent microtubules (MT) of the cell cortex. Confers MT resistance to the drug oryzalin. Promotes the formation of a planar network of antiparallel microtubules; Belongs to the MAP65/ASE1 family
Melanoma-associated antigen G1-like protein; Contains the following InterPro domains: MAGE protein (InterPro:IPR002190); Has 1274 Blast hits to 1260 proteins in 85 species: Archae - 0; Bacteria - 0; Metazoa - 1104; Fungi - 45; Plants - 49; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink)
Transcription regulatory protein SNF2, putative; ATPase subunit of a multiprotein complex equivalent of the SWI/SNF complex that acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. Represses embryonic genes in leaves and controls shoot development and flowering. Activates flower homeotic genes. The association of BRM with its target genes requires REF6. Necessary to acquire heat stress (HS) memory, by globally binding to HS memory genes
Somatic embryogenesis receptor-like kinase, putative; Protein kinase superfamily protein; Its function is described as protein tyrosine kinase activity, protein kinase activity, kinase activity, ATP binding; Involved in protein amino acid phosphorylation; Located in plasma membrane; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, active site (InterPro:IPR008266), Serine-threonine/tyrosine-pro [...]
FASCICLIN-like arabinogalactan protein 8; May be a cell surface adhesion protein; Belongs to the fasciclin-like AGP family
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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