STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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[Homology]
Score
AT3G44820BTB/POZ domain-containing protein At3g44820; May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (651 aa)    
Predicted Functional Partners:
AT4G08790
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase family protein; Its function is described as hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, nitrilase activity; Involved in response to cadmium ion, nitrogen compound metabolic process; Expressed in 21 plant structures; Expressed during 11 growth stages; Contains the following InterPro domains: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase (InterPro:IPR003010); BEST Arabidopsis thaliana protein match is: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase family prot [...]
      
 0.965
AT4G10320
tRNA synthetase class I (I, L, M and V) family protein; Its function is described as isoleucine-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, zinc ion binding, ATP binding; Involved in response to cadmium ion, tRNA aminoacylation for protein translation; Located in cytosol; Expressed in male gametophyte, guard cell, epidermis, cultured cell, pollen tube; Expressed during L mature pollen stage, M germinated pollen stage; Contains the following InterPro domains: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Isoleucyl-tRNA synthetase [...]
      
 0.840
AT1G11950
Transcription factor jumonji (jmjC) domain-containing protein; Contains the following InterPro domains: Transcription factor jumonji/aspartyl beta-hydroxylase (InterPro:IPR003347), Transcription factor jumonji (InterPro:IPR013129); BEST Arabidopsis thaliana protein match is: transcription factor jumonji (jmjC) domain-containing protein (TAIR:AT1G62310.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink)
      
 0.739
AT1G50000
Methyltransferases; Its function is described as methyltransferase activity; Involved in rRNA processing; Located in chloroplast; Expressed in 18 plant structures; Expressed during 9 growth stages; Contains the following InterPro domains: Pseudouridine synthase/archaeosine transglycosylase-like (InterPro:IPR015947), Ribosomal RNA small subunit methyltransferase E (InterPro:IPR006700); Has 5958 Blast hits to 5958 proteins in 2191 species: Archae - 0; Bacteria - 4231; Metazoa - 2; Fungi - 0; Plants - 34; Viruses - 0; Other Eukaryotes - 1691 (source: NCBI BLink)
      
 0.735
AT1G50020
Putative tubulin alpha-6 chain; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in chloroplast thylakoid membrane, chloroplast; Expressed in 24 plant structures; Expressed during 15 growth stages; Has 72 Blast hits to 72 proteins in 27 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 72; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink)
      
 0.735
AT2G42780
Transcription elongation factor B polypeptide; Its function is described as molecular_function unknown; Involved in regulation of transcription; Located in integral to membrane, nucleus; Expressed in 20 plant structures; Expressed during 11 growth stages; Contains the following InterPro domains: RNA polymerase II transcription factor SIII, subunit A (InterPro:IPR010684); Has 187 Blast hits to 186 proteins in 77 species: Archae - 0; Bacteria - 0; Metazoa - 104; Fungi - 29; Plants - 38; Viruses - 0; Other Eukaryotes - 16 (source: NCBI BLink)
      
 0.716
At4g25700
Beta-carotene 3-hydroxylase 1, chloroplastic; Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylations of beta-carotene. Has also a low activity toward the beta- and epsilon-rings of alpha-carotene. No activity with acyclic carotenoids such as lycopene and neurosporene. Uses ferredoxin as an electron donor (Probable); Belongs to the sterol desaturase family
      
 0.716
AT5G47070
Probable serine/threonine-protein kinase PBL19; May be involved in plant defense signaling
      
 0.641
BGLU14
Beta glucosidase 14 (BGLU14); Its function is described as cation binding, hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity; Involved in pollen tube growth; Located in plant-type cell wall; Expressed in stem, male gametophyte, pollen tube; Expressed during M germinated pollen stage; Contains the following InterPro domains: Glycoside hydrolase, family 1 (InterPro:IPR001360), Glycoside hydrolase, family 1, active site (InterPro:IPR018120), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); [...]
      
 0.570
RWP1
Omega-hydroxypalmitate O-feruloyl transferase; Involved in the synthesis of aromatics of the suberin polymer. Specifically affects the accumulation of the ferulate constituent of suberin in roots and seeds, but has no effect on the content of p-coumarate or sinapate
      
 0.543
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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