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JMJ14 protein (Arabidopsis thaliana) - STRING interaction network
"JMJ14" - JUMONJI 14 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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JMJ14JUMONJI 14; Histone demethylase that demethylates ’Lys-4’ (H3K4me) of histone H3 with a higher activity for H3K4me3 and H3K4me2 than H3K4me1. No activity on H3K9me3/2, H3K36me3/2 and H3K27me3/2. Represses FT and TSF expression to inhibit the floral transition. Binds around the transcription start site of the FT locus. Involved in the DRM2-mediated maintenance of DNA methylation, but not required for the de novo DNA methylation. Required for demethylating histone H3K4me3 at the target of RNA silencing (954 aa)    
Predicted Functional Partners:
NAC050
NAC domain containing protein 50 (526 aa)
     
 
  0.863
SUVH4
SU(VAR)3-9 homolog 4; Histone methyltransferase. Methylates ’Lys-9’ of histone H3. H3 ’Lys-9’ methylation represents a specific tag for epigenetic transcriptional repression. The silencing mechanism via DNA CpNpG methylation requires the targeting of chromomethylase CMT3 to methylated histones, probably through an interaction with an HP1-like adapter. By its function, KYP is directly required for the maintenance of the DNA CpNpG and asymmetric methylation. Involved in the silencing of transposable elements (624 aa)
     
 
  0.862
NAC052
NAC domain containing protein 52 (451 aa)
     
 
  0.854
SET27
Homologue of trithorax; Histone methyltransferase. Methylates ’Lys-4’ of histone H3. H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. Required to maintain the active state of class A (AP1 and AP2), class B (PI and AP3) and class C (AG) floral homeotic genes at early stages of flower development. Regulates floral organ identity and flowering transition. Functions as a receptor for the lipid messenger phosphatidylinositol 5-phosphate (PI5P), which regulates negatively its transcriptional activation activity (1062 aa)
     
 
  0.828
SDG16
SET domain protein 16; Histone methyltransferase (1027 aa)
     
 
  0.809
ATX2
Trithorax-like protein 2; Histone methyltransferase (1083 aa)
     
 
  0.787
TRO
TRAUCO; Trithorax-group gene homolog required for early embryogenesis (PubMed-20118203, PubMed-21423667). Required for the expression of FLC and FLC homologs and represses flowering (PubMed-21423667). Required for proper leaf growth and development (PubMed-21423667). Part of COMPASS-like complexes responsible for H3K4 trimethylation, but not for di- or mono-methylation of histone H3 ’Lys-4’ (PubMed-21423667). Binds to target loci chromatin, increasing H3K4 trimethylation and causing activation of the gene (PubMed-21423667) (509 aa)
     
 
  0.781
HAT3.1
Homeobox protein HAT3.1; Binds only to large DNA fragments. Recognizes a DNA fragment carrying 8 copies of box7 motif of the light-induced cab- E promoter of Nicotiana plumbaginifolia. Also recognizes the box7m1 motif (723 aa)
     
 
  0.776
SUVH5
SU(VAR)3-9 homolog 5; Histone methyltransferase. Methylates ’Lys-9’ of histone H3. H3 ’Lys-9’ methylation represents a specific tag for epigenetic transcriptional repression (794 aa)
     
 
  0.773
SDG14
SET domain protein 14; Histone methyltransferase (1018 aa)
     
 
  0.765
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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