• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
ATR1 protein (Arabidopsis thaliana) - STRING interaction network
"ATR1" - NADPH--cytochrome P450 reductase 1 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATR1NADPH--cytochrome P450 reductase 1; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and dichloroindophenol; Belongs to the NADPH--cytochrome P450 reductase family (692 aa)    
Predicted Functional Partners:
SIR
Assimilatory sulfite reductase (ferredoxin), chloroplastic; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (642 aa)
 
  0.911
NIR1
Ferredoxin--nitrite reductase, chloroplastic; Involved in the second step of nitrate assimilation. Its expression is induced by nitrate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (586 aa)
   
 
  0.883
NIA1
Nitrate reductase [NADH] 1; Encodes the cytosolic minor isoform of nitrate reductase (NR). Involved in the first step of nitrate assimilation, it contributes about 15% of the nitrate reductase activity in shoots. Similar to molybdopterin oxidoreductases at the N-terminus, and to FAD/NAD-binding cytochrome reductases at the C-terminus. Cofactors- FAD, heme iron (cytochrome B-557), and molybdenum-pterin (917 aa)
   
 
  0.764
NIA2
Nitrate reductase [NADH] 2; Identified as a mutant resistant to chlorate. Encodes nitrate reductase structural gene. Involved in nitrate assimilation. Has nitrate reductase activity. Up-regulated by the fungus P. indica. Binds transcription factor At2g35940 (917 aa)
   
 
  0.764
AT2G24580
FAD-dependent oxidoreductase family protein; Its function is described as sarcosine oxidase activity; Involved in tetrahydrofolate metabolic process, oxidation reduction; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- FAD dependent oxidoreductase (InterPro-IPR006076), Sarcosine oxidase, monomeric (InterPro-IPR006281); Has 4031 Blast hits to 4005 proteins in 935 species- Archae - 135; Bacteria - 2670; Metazoa - 148; Fungi - 247; Plants - 60; Viruses - 0; Other Eukaryotes - 771 (source- [...] (416 aa)
           
  0.716
EMB2804
Tubulin-folding cofactor B; Involved in control of cell division. Regulates probably the availability of alpha-tubulin for dimerization of alpha-/beta- tubulin, which is required for proper microtubule biogenesis. Decreased expression of TFCB results in enlarged mesophyll cells and leaf epidermal cells with bulged nuclei, increased ploidy and increased numbers of spindles and phragmoplasts (243 aa)
     
   
  0.709
FD3
Ferredoxin-3, chloroplastic; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions; Belongs to the 2Fe2S plant-type ferredoxin family (155 aa)
     
 
  0.706
AT5G20080
NADH-cytochrome b5 reductase-like protein; Desaturation and elongation of fatty acids; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (328 aa)
   
 
  0.699
UPM1
Encodes a urophorphyrin III methylase that catalyzes S-adenosyl-L-methionine-dependent transmethylation in a multistep process involving the formation of a covalently linked complex with S-adenosyl-L-methionine; Belongs to the precorrin methyltransferase family (369 aa)
   
   
  0.695
APS4
Pseudouridine synthase/archaeosine transglycosylase-like family protein; Sulfate adenylyltransferase, ATP sulfurylase (469 aa)
   
   
  0.685
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (20%) [HD]