STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurence
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[Homology]
Score
GAE1UDP-D-glucuronate 4-epimerase 1; Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components (429 aa)    
Predicted Functional Partners:
AT5G18200
UDPglucose--hexose-1-phosphate uridylyltransferase; Catalyzes the conversion of ADP-glucose and inorganic phosphate (Pi) into glucose-1-phosphate and ADP. Does not possess galactose-1-phosphate uridylyltransferase activity
  
 0.980
USP
UDP-sugar pyrophosphorylase; Required for the synthesis of the intine, the pectocellulosic inner wall of developing pollen. May function as the terminal enzyme of the myo-inositol oxidation (MIO) pathway. May also play a role in the salvage pathway for synthesis of nucleotide sugars. Can use a wide range of substrates including glucose-1-phosphate, galactose-1-phosphate, xylose-1-phosphate, arabinose-1-phosphate and glucuronate-1-phosphate
  
 
 0.941
UGP1
UTP--glucose-1-phosphate uridylyltransferase 2; Converts glucose 1-phosphate to UDP-glucose, which is the major glycosyl donor for polysaccharides. Acts redundantly with UGP1 and is essential for the synthesis of sucrose, starch and cell wall, and callose deposition; Belongs to the UDPGP type 1 family
  
 
 0.922
UGD1
UDP-glucose 6-dehydrogenase 1; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers
 
 
 0.907
UGP2
UTP--glucose-1-phosphate uridylyltransferase 1; Converts glucose 1-phosphate to UDP-glucose, which is the major glycosyl donor for polysaccharides. Acts redundantly with UGP2 and is essential for the synthesis of sucrose, starch and cell wall, and callose deposition. Involved in the regulation of the programmed cell death (PCD) induced by the fungal toxin fumonisin B1 (FB1)
  
 
 0.880
ULI3
Cysteine/Histidine-rich C1 domain family protein; Isolated in a screen for UV-B insensitive mutants using a hypocotyl growth inhibition assay. Mutants are defective in a number of UV-B responses
      
 0.829
GBSS1
Granule-bound starch synthase 1, chloroplastic/amyloplastic; Required for the synthesis of amylose. Destroyed as it is released from the starch granules during the night. The circadian expression is controlled by CCA1 and LHY transcription factors
    
 0.805
AT4G29680
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3; Alkaline-phosphatase-like family protein; Its function is described as hydrolase activity, catalytic activity; Involved in metabolic process, nucleotide metabolic process; Located in vacuole; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Alkaline phosphatase-like, alpha/beta/alpha (InterPro:IPR017849), Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (InterPro:IPR002591), Alkaline-phosphatase-like, core domain (InterPro:IPR017850); [...]
   
 
  0.800
UGD2
UDP-glucose 6-dehydrogenase family protein; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. Required for the formation of cell wall ingrowths on the outer cell walls of nematode-induced syncytia; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family
 
 
 0.797
AT3G01010
UDP-glucose/GDP-mannose dehydrogenase family protein; Its function is described as NAD or NADH binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; Involved in oxidation reduction; Located in endomembrane system; Expressed in cultured cell; Contains the following InterPro domains: UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding domain (InterPro:IPR014028), UDP-glucose/GDP-mannose dehydrogenase, C-terminal (InterPro:IPR014027); BEST Arabidopsis thaliana protein match is: UDP-glucose 6-dehydrogenase family protein (TAIR [...]
  
 
 0.794
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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