STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT5G03820GDSL-like Lipase/Acylhydrolase family protein; Its function is described as hydrolase activity, acting on ester bonds, lipase activity, carboxylesterase activity; Involved in lipid metabolic process; Located in endomembrane system; Contains the following InterPro domains: Lipase, GDSL, active site (InterPro:IPR008265), Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: GDSL-like Lipase/Acylhydrolase family protein (TAIR:AT5G03810.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Virus [...] (354 aa)    
Predicted Functional Partners:
AT4G33600
Uncharacterized protein At4g33600/T16L1_90; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; Expressed in 6 plant structures; Expressed during 4 anthesis, C globular stage, petal differentiation and expansion stage; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT4G33590.1); Has 131 Blast hits to 131 proteins in 40 species: Archae - 0; Bacteria - 9; Metazoa - 12; Fungi - 24; Plants - 58; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink)
   
  
 0.968
AT3G26630
Pentatricopeptide repeat-containing protein At3g26630, chloroplastic; Tetratricopeptide repeat (TPR)-like superfamily protein; Contains the following InterPro domains: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Pentatricopeptide repeat (PPR-like) superfamily protein (TAIR:AT2G42920.1); Has 33140 Blast hits to 12409 proteins in 168 species: Archae - 0; Bacteria - 0; Metazoa - 3; Fungi - 38; Plants - 32761; Viruses - 0; Other Eukaryotes - 338 (source: NCBI BLink)
      
 0.952
RGE1
Basic helix-loop-helix (bHLH) DNA-binding superfamily protein; Transcription factor that controls embryo growth. Regulates endosperm breakdown and embryonic epidermal development. Regulates the expression of SBT2.4/ALE1. Involved in embryonic cuticle formation upstream of SBT2.4/ALE1. Does not seem to be a general regulator of endosperm patterning. May control specific signaling pathways that coordinate embryo invasion and breakdown of surrounding endosperm tissues. Required for the production the embryo sheath, an extracuticular endosperm-derived structure at the surface of the embryo [...]
   
  
 0.910
AT3G06890
Uncharacterized protein At3g06890; Unknown protein; Has 91 Blast hits to 91 proteins in 12 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 91; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink)
      
 0.899
MLP423
MLP-like protein 423 (MLP423); Involved in response to biotic stimulus, defense response; Expressed in 22 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains: Bet v I allergen (InterPro:IPR000916); BEST Arabidopsis thaliana protein match is: MLP-like protein 28 (TAIR:AT1G70830.3)
   
    0.751
ALE1
PA-domain containing subtilase family protein; Serine protease required for epidermal surface formation in embryos and juvenile plants. Involved in embryonic cuticle formation downstream of BHLH95/ZOU; Belongs to the peptidase S8 family
   
  
 0.712
LWD2
Transducin/WD40 repeat-like superfamily protein; Clock protein essential for the proper expression phase and period length of both the oscillator and output genes known to participate in photoperiod sensing. Required for the expression of APRR9, APRR7, and APRR5. Regulated by APRR9 and APRR7 at the transcriptional level, indicating the existence of a positive feedback loop within the circadian clock
      
 0.699
HB51
Putative homeobox-leucine zipper protein ATHB-51; Encodes a homeodomain leucine zipper class I (HD-Zip I) meristem identity regulator that acts together with LFY to induce CAL expression. It binds to the CAL promoter proximal CAATNATTG element. LMI1 acts primarily downstream of LFY in meristem identity regulation. The interaction between LFY, LMI1 and CAL resembles a feed-forward loop transcriptional network motif. The gene also had additional LFY-independent roles in leaf morphogenesis and bract formation
      
 0.658
AT3G27325
Hydrolases, acting on ester bonds; Its function is described as hydrolase activity, acting on ester bonds; Involved in intracellular protein transport, GPI anchor metabolic process; Located in endoplasmic reticulum; Expressed in 20 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains: PGAP1-like (InterPro:IPR012908)
      
 0.628
OMR1
Threonine dehydratase biosynthetic, chloroplastic; Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia; Belongs to the serine/threonine dehydratase family
      
 0.478
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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