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LOG8 protein (Arabidopsis thaliana) - STRING interaction network
"LOG8" - Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG8 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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LOG8Cytokinin riboside 5’-monophosphate phosphoribohydrolase LOG8; Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (216 aa)    
Predicted Functional Partners:
THY-2
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (565 aa)
   
        0.894
AT2G21550
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (492 aa)
   
        0.894
THY-1
Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (519 aa)
   
        0.894
AT5G09720
Magnesium transporter CorA-like family protein; BEST Arabidopsis thaliana protein match is- magnesium transporter 7 (TAIR-AT5G09690.3); Has 601 Blast hits to 596 proteins in 130 species- Archae - 0; Bacteria - 0; Metazoa - 46; Fungi - 173; Plants - 356; Viruses - 0; Other Eukaryotes - 26 (source- NCBI BLink); Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family (294 aa)
     
   
  0.739
PI-4KBETA2
Phosphatidylinositol 4-OH kinase beta2; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5-trisphosphate (By similarity). Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB1, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB1 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway (1116 aa)
     
   
  0.700
CYP735A2
Cytochrome P450, family 735, subfamily A, polypeptide 2; Cytokinin hydroxylase that catalyzes the biosynthesis of trans-zeatin via the isopentenyladenine riboside 5’-monophosphate (iPRMP)-dependent pathway. Can use isopentenyladenosine-5’- monophosphate, isopentenyladenosine-5’-diphosphate and isopentenyladenosine-5’-triphosphate as substrate (512 aa)
           
  0.642
CYP735A1
Cytochrome P450, family 735, subfamily A, polypeptide 1; Cytokinin hydroxylase that catalyzes the biosynthesis of trans-zeatin via the isopentenyladenine riboside 5’-monophosphate (iPRMP)-dependent pathway. Can use isopentenyladenosine-5’- monophosphate, isopentenyladenosine-5’-diphosphate and isopentenyladenosine-5’-triphosphate as substrate (518 aa)
           
  0.639
IPT1
Encodes a putative adenylate isopentenyltransferase. It catalyzes the formation of isopentenyladenosine 5’-monophosphate (iPMP) from AMP and dimethylallylpyrophosphate (DMAPP), but it has a lower Km for ADP and likely works using ADP or ATP in plants. It is involved in cytokinin biosynthesis (357 aa)
         
  0.628
DEG15
Glyoxysomal processing protease, glyoxysomal; Trypsin-like serine endopeptidase involved in the processing of glyoxysomal higher molecular weight precursor. The dimeric form carries out the specific cleavages needed to remove PTS2-containing presequences, whereas the monomeric form degrades the removed presequences and misfolded proteins (Probable). Not required for degradation of glyoxylate cycle enzymes during seedling development (709 aa)
   
   
  0.584
RAP2.7
Ethylene-responsive transcription factor RAP2-7; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay; Belongs to the AP2/ERF transcription factor family. AP2 subfamily (464 aa)
           
  0.576
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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