STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRF714-3-3-like protein GF14 nu; Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. (265 aa)    
Predicted Functional Partners:
F28N24.7
Alba DNA/RNA-binding protein.
      
 0.738
CDC25
Dual specificity phosphatase Cdc25; Tyrosine protein phosphatase that dephosphorylates CDK complex and activate its kinase activity in vitro. Belongs to the MPI phosphatase family.
    
 0.729
UPL5
E3 ubiquitin-protein ligase UPL5; E3 ubiquitin protein ligase that regulates leaf senescence through ubiquitination and subsequent degradation of WRKY53.
    
 0.681
COX5B-2
Cytochrome c oxidase subunit 5b-2, mitochondrial; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport; Belongs to the cytochrome c oxidase subunit 5B (TC 3.D.4.11) family.
   
  
 0.606
NF-YB11
Putative CCAAT-binding transcription factor subunit.
   
  
 0.600
CINV1
Alkaline/neutral invertase CINV1; Cytosolic invertase that specifically cleaves sucrose into glucose and fructose and is involved in the regulation of multiple tissue development including primary root elongation, root hair growth, leaf and silique development, and floral transition. Is involved in osmotic stress-induced inhibition on lateral root growth by controlling the concentration of hexose in cells. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells. Belongs to the glycosyl hydrolase 100 family.
    
   0.588
TSF
Protein TWIN SISTER of FT; May form complexes with phosphorylated ligands by interfering with kinases and their effectors; Belongs to the phosphatidylethanolamine-binding protein family.
    
 0.584
FT
Protein FLOWERING LOCUS T; Component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. Translated in leaves and then transported to the shoot apical meristem where it activates the transcription of several floral meristem identity genes. May play a role in both the autonomous and the long-day flowering pathways.
    
 0.584
MT1A
Metallothionein-like protein 1A; Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable). Functions as metal chelator of copper (Cu) and zinc (Zn). Plays a role in Cu homeostasis in the roots under elevated Cu concentration. Functions cooperatively with the phytochelatin synthase PCS1 to protect plants from Cu and cadmium (Cd) toxicity. Plays a role in Cu homeostasis, specifically in the remobilization of Cu from senescing leaves. The mobilization of Cu from internal sources is important for seed development. Confers tolerance to Cd and plays [...]
      
 0.573
BT4
BTB/POZ and TAZ domain-containing protein 4; May act as a substrate-specific adapter of an E3 ubiquitin- protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    
 
 0.554
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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