STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PaaK-2Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (447 aa)    
Predicted Functional Partners:
CaiC-2
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
 0.742
CaiC-4
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
     
 0.742
PTH_2653
ACT domain-containing protein.
 
   0.698
PaaI
Uncharacterized protein; Possibly involved in aromatic compounds catabolism.
 
  
 0.676
PTH_1584
Putative aldehyde/alcohol dehydrogenase; Containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.629
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
  
 0.508
RelE
Cytotoxic translational repressor; Toxin-antitoxin stability system.
      
 0.497
UbiD
3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.
      
 0.497
UbiD-2
3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.
      
 0.497
MhpF
Acetaldehydede hydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
      
 0.454
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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