STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
NifS-2Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (402 aa)    
Predicted Functional Partners:
IscU-2
NifU homolog; Involved in Fe-S cluster formation.
 
 0.996
IscU
NifU homolog; Involved in Fe-S cluster formation.
 
 0.983
SirA-2
Predicted redox protein; Regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
   
 0.970
SirA-4
Predicted redox protein; Regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.
   
 0.970
ThiF
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.943
ThiF-2
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.943
ThiF-3
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
   
 0.943
SseA
Rhodanese-related sulfurtransferase.
   
 0.916
SseA-2
Rhodanese-related sulfurtransferase.
   
 0.916
SseA-3
Rhodanese-related sulfurtransferase.
   
 0.916
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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