node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CafA | PTH_1236 | PTH_0829 | PTH_1236 | Ribonucleases G and E. | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.525 |
CafA | Pnp-2 | PTH_0829 | PTH_1275 | Ribonucleases G and E. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.891 |
CafA | Rho | PTH_0829 | PTH_2835 | Ribonucleases G and E. | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.509 |
InfB | NusA | PTH_1269 | PTH_1266 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Transcription elongation factor; Participates in both transcription termination and antitermination. | 0.994 |
InfB | PTH_1236 | PTH_1269 | PTH_1236 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.670 |
InfB | Pnp-2 | PTH_1269 | PTH_1275 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.855 |
InfB | Rho | PTH_1269 | PTH_2835 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.608 |
InfB | RplD | PTH_1269 | PTH_0321 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.963 |
InfB | RpoB | PTH_1269 | PTH_0312 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.981 |
InfB | RpsO | PTH_1269 | PTH_1274 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Ribosomal protein S15P/S13E; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.928 |
InfB | TruB | PTH_1269 | PTH_1272 | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.990 |
NusA | InfB | PTH_1266 | PTH_1269 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Translation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.994 |
NusA | PTH_1236 | PTH_1266 | PTH_1236 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.429 |
NusA | Pnp-2 | PTH_1266 | PTH_1275 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.871 |
NusA | Rho | PTH_1266 | PTH_2835 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.919 |
NusA | RplD | PTH_1266 | PTH_0321 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.911 |
NusA | RpoB | PTH_1266 | PTH_0312 | Transcription elongation factor; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.971 |
NusA | RpsO | PTH_1266 | PTH_1274 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Ribosomal protein S15P/S13E; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.820 |
NusA | TruB | PTH_1266 | PTH_1272 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.887 |
NusA | rny | PTH_1266 | PTH_1302 | Transcription elongation factor; Participates in both transcription termination and antitermination. | Hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.406 |