STRINGSTRING
Bra004822 protein (Brassica rapa) - STRING interaction network
"Bra004822" - AT2G44270 in Brassica rapa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bra004822AT2G44270 (E=3e-123) | ATP binding ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (399 aa)    
Predicted Functional Partners:
Bra011714
AT4G35910 (E=8e-211) | unknown protein ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (448 aa)
     
  0.996
Bra027795
AT1G63660 (E=6e-286) | GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase, putative (530 aa)
       
  0.925
Bra000397
AT2G45695 (E=8e-040) | FUNCTIONS IN- molecular_function unknown; INVOLVED IN- biological_process unknown; LOCATED IN- cellular_component unknown; CONTAINS InterPro DOMAIN/s- Ubiquitin related modifier 1 (InterPro-IPR015221), Ubiquitin-related modifier 1 (InterPro-IPR017188), Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp (InterPro-IPR016155); BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT3G61113.1); Has 238 Blast hits to 238 proteins in 125 species- Archae - 0; Bacteria - 0; Metazoa - 93; Fungi - 72; Plants - 18; Viruses - 0; Other Eukaryo [...] (99 aa)
       
  0.855
Bra000619
AT5G50320 (E=1e-306) ELO3, HAG3, HAC8 | ELO3 (ELONGATA 3); histone acetyltransferase (565 aa)
     
 
  0.821
Bra028243
AT4G26900 (E=1e-277) AT-HF, HISN4 | AT-HF (HIS HF); imidazoleglycerol-phosphate synthase (585 aa)
   
 
  0.772
Bra026393
AT4G26900 (E=2e-166) AT-HF, HISN4 | AT-HF (HIS HF); imidazoleglycerol-phosphate synthase (581 aa)
   
 
  0.772
Bra035556
AT5G55130 (E=4e-240) CNX5, SIR1 | CNX5 (CO-FACTOR FOR NITRATE, REDUCTASE AND XANTHINE DEHYDROGENASE 5); Mo-molybdopterin cofactor sulfurase ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thi [...] (470 aa)
     
 
  0.665
Bra002930
AT5G55130 (E=3e-242) CNX5, SIR1 | CNX5 (CO-FACTOR FOR NITRATE, REDUCTASE AND XANTHINE DEHYDROGENASE 5); Mo-molybdopterin cofactor sulfurase ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thi [...] (466 aa)
     
 
  0.665
Bra009004
AT5G10920 (E=1e-258) | argininosuccinate lyase, putative / arginosuccinase, putative (940 aa)
       
  0.605
Bra038428
AT2G21410 (E=4e-024) VHA-A2 | VHA-A2 (VACUOLAR PROTON ATPASE A2); ATPase (537 aa)
   
   
  0.584
Your Current Organism:
Brassica rapa
NCBI taxonomy Id: 3711
Other names: B. rapa, Brassica, Brassica L., Brassica rapa, Brassica rapa L., Brassiceae, field mustard
Server load: low (8%) [HD]