STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose (403 aa)    
Predicted Functional Partners:
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate
 
 0.995
rpiA
Ribose 5-phosphate isomerase a; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate
    
 0.984
deoD
Purine nucleoside phosphorylase DeoD-type; Equivalent gene in S.pneumoniae TIGR4 = SP0835; equivalent gene in S.pneumoniae R6 = spr0738; identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107
 
 
 0.983
SPD_0726
Purine nucleoside phosphorylase, family protein 2; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
    
 0.973
pdp
Pyrimidine-nucleoside phosphorylase; Equivalent gene in S.pneumoniae TIGR4 = SP0842; equivalent gene in S.pneumoniae R6 = spr0744; identified by match to protein family HMM PF00591; match to protein family HMM PF02885; match to protein family HMM PF07831; match to protein family HMM TIGR02644
 
 
 0.973
prs2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P)
     
 0.967
SPD_0875
Hydrolase, NUDIX family protein; Equivalent gene in S.pneumoniae TIGR4 = SP0989; equivalent gene in S.pneumoniae R6 = spr0892; identified by match to protein family HMM PF00293
    
  0.933
pgm
Phosphoglucomutase/phosphomannomutase family protein; Equivalent gene in S.pneumoniae TIGR4 = SP1498; equivalent gene in S.pneumoniae R6 = spr1351; identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880
    
 0.931
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P)
     
 0.916
SPD_1958
Transketolase N-terminal subunit; Equivalent gene in S.pneumoniae TIGR4 = SP2128; equivalent gene in S.pneumoniae R6 = spr1937; identified by match to protein family HMM PF00456
    
 0.905
Your Current Organism:
Streptococcus pneumoniae D39
NCBI taxonomy Id: 373153
Other names: S. pneumoniae D39, Streptococcus pneumoniae str. D39, Streptococcus pneumoniae strain D39
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