STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcsBArginine kinase; Catalyzes the specific phosphorylation of arginine residues in proteins. (349 aa)    
Predicted Functional Partners:
ACL68846.1
PFAM: UvrB/uvrC motif.
 
  
 0.997
ACL68845.1
Transcriptional repressor, CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family.
 
  
 0.981
ACL68848.1
ATPase AAA-2 domain protein; PFAM: UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); Clp amino terminal domain; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); Belongs to the ClpA/ClpB family.
 
 
 0.964
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.767
disA
Predicted nucleic-acid-binding protein (contains the HHH domain); Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
    0.722
ACL68852.1
PilT protein domain protein; PFAM: PIN domain; TRAM domain.
  
    0.518
ACL68844.1
Uncharacterized conserved protein.
 
     0.498
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
  
    0.459
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.416
ACL68851.1
Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain.
       0.411
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.