node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACL69013.1 | murB | Hore_02520 | Hore_22190 | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.404 |
ACL69013.1 | murC | Hore_02520 | Hore_09100 | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.586 |
ACL69013.1 | murG | Hore_02520 | Hore_09090 | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.417 |
ACL69013.1 | murI | Hore_02520 | Hore_02590 | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.610 |
ACL69632.1 | murF | Hore_08760 | Hore_09050 | Cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.403 |
ACL69632.1 | murG | Hore_08760 | Hore_09090 | Cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.572 |
ACL69632.1 | murI | Hore_08760 | Hore_02590 | Cell divisionFtsK/SpoIIIE; PFAM: FtsK/SpoIIIE family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.652 |
ACL70287.1 | murI | Hore_15380 | Hore_02590 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.926 |
ddl | murB | Hore_08980 | Hore_22190 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.997 |
ddl | murC | Hore_08980 | Hore_09100 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.985 |
ddl | murD | Hore_08980 | Hore_09070 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.898 |
ddl | murF | Hore_08980 | Hore_09050 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddl | murG | Hore_08980 | Hore_09090 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.918 |
ddl | murI | Hore_08980 | Hore_02590 | D-alanine--D-alanine ligase; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.676 |
murB | ACL69013.1 | Hore_22190 | Hore_02520 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Belongs to the phosphohexose mutase family. | 0.404 |
murB | ddl | Hore_22190 | Hore_08980 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | D-alanine--D-alanine ligase; Cell wall formation. | 0.997 |
murB | murC | Hore_22190 | Hore_09100 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
murB | murD | Hore_22190 | Hore_09070 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.959 |
murB | murF | Hore_22190 | Hore_09050 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.880 |
murB | murG | Hore_22190 | Hore_09090 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.921 |