STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (322 aa)    
Predicted Functional Partners:
ACL70827.1
PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S binding domain; 4Fe-4S binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
  
 0.994
ACL69083.1
Pyruvate kinase; PFAM: PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.988
ACL69286.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.966
ACL69763.1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, N-terminal domain; Malic enzyme, NAD binding domain.
  
 0.963
ACL71062.1
PFAM: Pyruvate formate lyase; Glycine radical; TIGRFAM: formate acetyltransferase 1.
   
 
 0.947
ACL69435.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain; Transketolase, C-terminal domain.
  
 
 0.936
ACL70817.1
PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain.
  
 
 0.936
ACL70022.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.933
ACL69287.1
Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family.
  
 
 0.926
ACL69436.1
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
  
 
 0.926
Your Current Organism:
Halothermothrix orenii
NCBI taxonomy Id: 373903
Other names: H. orenii H 168, Halothermothrix orenii H 168, Halothermothrix orenii str. H 168, Halothermothrix orenii strain H 168
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