node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY53579.1 | AFY54734.1 | Riv7116_1004 | Riv7116_2211 | Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.910 |
AFY53579.1 | AFY54742.1 | Riv7116_1004 | Riv7116_2219 | Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. | FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. | 0.929 |
AFY54734.1 | AFY53579.1 | Riv7116_2211 | Riv7116_1004 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. | 0.910 |
AFY54734.1 | AFY54742.1 | Riv7116_2211 | Riv7116_2219 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. | 0.910 |
AFY54734.1 | AFY55383.1 | Riv7116_2211 | Riv7116_2886 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Threonine aldolase; PFAM: Beta-eliminating lyase. | 0.933 |
AFY54734.1 | AFY56867.1 | Riv7116_2211 | Riv7116_4446 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | 0.933 |
AFY54734.1 | AFY58335.1 | Riv7116_2211 | Riv7116_5974 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.912 |
AFY54734.1 | gcvH | Riv7116_2211 | Riv7116_3511 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.921 |
AFY54734.1 | gcvP | Riv7116_2211 | Riv7116_3510 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.936 |
AFY54734.1 | gcvT | Riv7116_2211 | Riv7116_3512 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.945 |
AFY54734.1 | glyA | Riv7116_2211 | Riv7116_4195 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.936 |
AFY54734.1 | ilvA | Riv7116_2211 | Riv7116_5332 | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.925 |
AFY54742.1 | AFY53579.1 | Riv7116_2219 | Riv7116_1004 | FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. | Glycolate oxidase, subunit GlcD; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD. | 0.929 |
AFY54742.1 | AFY54734.1 | Riv7116_2219 | Riv7116_2211 | FAD/FMN-dependent dehydrogenase; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.910 |
AFY55383.1 | AFY54734.1 | Riv7116_2886 | Riv7116_2211 | Threonine aldolase; PFAM: Beta-eliminating lyase. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.933 |
AFY55383.1 | gcvP | Riv7116_2886 | Riv7116_3510 | Threonine aldolase; PFAM: Beta-eliminating lyase. | Glycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.943 |
AFY55383.1 | glyA | Riv7116_2886 | Riv7116_4195 | Threonine aldolase; PFAM: Beta-eliminating lyase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.934 |
AFY55383.1 | ilvA | Riv7116_2886 | Riv7116_5332 | Threonine aldolase; PFAM: Beta-eliminating lyase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.921 |
AFY56867.1 | AFY54734.1 | Riv7116_4446 | Riv7116_2211 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V. | 0.933 |
AFY56867.1 | gcvP | Riv7116_4446 | Riv7116_3510 | PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB. | Glycine dehydrogenase, decarboxylating; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.462 |