STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. (559 aa)    
Predicted Functional Partners:
Kcr_0360
PFAM: t-RNA-binding domain protein; KEGG: pab:PAB0278 fragment of methionyl-tRNA synthetase.
 
  
 0.947
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: hbu:Hbut_1241 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.922
Kcr_1091
PFAM: Methionine synthase vitamin-B12 independent; Cobalamin-independent synthase MetE domain protein; KEGG: smr:Smar_0416 methionine synthase II (cobalamin-independent)-like protein.
    
 0.909
Kcr_0033
PFAM: t-RNA-binding domain protein; KEGG: mtp:Mthe_0888 methionyl-tRNA synthetase.
 
      0.900
argS
KEGG: tpe:Tpen_0564 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.890
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 0.882
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
  
 0.843
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
 0.813
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.801
Kcr_1130
TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein; thiamine biosynthesis protein; KEGG: pcl:Pcal_1723 GMP synthase, large subunit.
  
  
 0.726
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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