STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBTIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: tpe:Tpen_1157 aspartate carbamoyltransferase. (296 aa)    
Predicted Functional Partners:
Kcr_0151
KEGG: tpe:Tpen_1159 dihydroorotase, multifunctional complex type; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase.
 0.999
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.992
Kcr_0156
PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: tpe:Tpen_1147 orotidine 5'-phosphate decarboxylase.
  
  
 0.991
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.969
Kcr_0152
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: tpe:Tpen_1160 oxidoreductase FAD/NAD(P)-binding domain protein.
  
  
 0.966
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 0.963
argG
PFAM: argininosuccinate synthase; KEGG: hbu:Hbut_0305 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.916
Kcr_0338
PFAM: aminotransferase class I and II; KEGG: tpe:Tpen_1417 aminotransferase, class I and II.
    
 0.908
Kcr_0953
PFAM: aminotransferase class I and II; KEGG: aae:aq_1969 aspartate aminotransferase.
    
 0.908
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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