STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kcr_0521TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: tpe:Tpen_0611 threonine dehydratase. (401 aa)    
Predicted Functional Partners:
ilvD
KEGG: pab:PAB0895 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.975
Kcr_0641
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: pcl:Pcal_1753 acetolactate synthase, large subunit, biosynthetic type.
  
 0.966
Kcr_0665
Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sso:SSO0493 threonine synthase.
 
 
0.954
Kcr_0354
Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tpe:Tpen_1537 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
0.951
Kcr_0993
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
0.951
Kcr_1035
Threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hbu:Hbut_1034 hypothetical protein.
  
 
 0.951
Kcr_0190
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mka:MK0782 isocitrate/isopropylmalate dehydrogenase.
  
 
 0.943
Kcr_0831
PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: rba:RB8979 probable L-serine dehydratase, alpha chain.
  
 
 0.943
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.930
Kcr_1154
TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ape:APE_0683 phosphoserine phosphatase.
    
 0.925
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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