STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyaRGlyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pho:PH0597 D-3-phosphoglycerate dehydrogenase. (332 aa)    
Predicted Functional Partners:
Kcr_1277
Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: tpe:Tpen_0207 hydroxypyruvate reductase.
 
 
 0.961
Kcr_0942
PFAM: FAD linked oxidase domain protein; KEGG: tac:Ta0542 putative glycolate oxidase.
   
 0.936
Kcr_1187
PFAM: FAD linked oxidase domain protein; KEGG: dps:DP0059 probable glycolate oxidase subunit (GlcD).
   
 0.936
Kcr_1188
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: afu:AF0506 iron-sulfur binding reductase.
    
 0.914
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.575
Kcr_0150
KEGG: chy:CHY_1144 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.551
rpl4
Ribosomal protein L4; Forms part of the polypeptide exit tunnel.
  
 
 0.551
Kcr_1549
PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; KEGG: sto:ST0557 elongation factor EF-1 alpha subunit.
     
 0.532
Kcr_1500
KEGG: mse:Msed_1652 glyceraldehyde-3-phosphate dehydrogenase, type II.
  
  
 0.502
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.491
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeum cryptofilum OPF8, korarchaeote OPF1-KOR
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