STRINGSTRING
eIF5A protein (Korarchaeum cryptofilum) - STRING interaction network
"eIF5A" - Translation initiation factor eIF-5A in Korarchaeum cryptofilum
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eIF5ATranslation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond (134 aa)    
Predicted Functional Partners:
Kcr_1377
50S ribosomal protein L15e (195 aa)
   
   
  0.999
rpl21e
50S ribosomal protein L21e (98 aa)
 
   
  0.993
Kcr_0120
50S ribosomal protein L16 (131 aa)
 
   
  0.983
Kcr_0505
Deoxyhypusine synthase (310 aa)
   
  0.980
rpl44e
50S ribosomal protein L44E; Binds to the 23S rRNA (92 aa)
   
   
  0.977
rps17e
30S ribosomal protein S17 (67 aa)
     
   
  0.971
Kcr_1570
30S ribosomal protein S5 (210 aa)
     
 
  0.959
rpl5
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (185 aa)
     
   
  0.951
rpl6
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (182 aa)
     
   
  0.946
srp54
GTP-binding signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (437 aa)
   
 
  0.944
Your Current Organism:
Korarchaeum cryptofilum
NCBI taxonomy Id: 374847
Other names: C. Korarchaeum, C. Korarchaeum cryptofilum, C. Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum, Candidatus Korarchaeum cryptofilum, Candidatus Korarchaeum cryptofilum OPF8, Candidatus Korarchaeum cryptofilum str. OPF8, Candidatus Korarchaeum cryptofilum strain OPF8, Korarchaeota, Korarchaeum, Korarchaeum cryptofilum, Korarchaeum cryptofilum OPF8, Xenarchaea, Xenarchaeota, korarchaeote OPF1-KOR
Server load: low (3%) [HD]