node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RD1_0686 | alsS | RD1_0686 | RD1_1674 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | 0.422 |
RD1_0686 | ilvB-2 | RD1_0686 | RD1_2449 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Acetolactate synthase; Belongs to the TPP enzyme family. | 0.456 |
RD1_0686 | ilvB-3 | RD1_0686 | RD1_2812 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Acetolactate synthase, large subunit. | 0.693 |
RD1_0686 | ilvC | RD1_0686 | RD1_1954 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.981 |
RD1_0686 | ilvD | RD1_0686 | RD1_0332 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.922 |
RD1_0686 | ilvN | RD1_0686 | RD1_2813 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | Acetolactate synthase, small subunit. | 0.641 |
RD1_0686 | leuB | RD1_0686 | RD1_0228 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.668 |
RD1_0686 | leuC | RD1_0686 | RD1_0616 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.771 |
RD1_0686 | leuD | RD1_0686 | RD1_0226 | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.653 |
alsS | RD1_0686 | RD1_1674 | RD1_0686 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | 0.422 |
alsS | ilvB-2 | RD1_1674 | RD1_2449 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Acetolactate synthase; Belongs to the TPP enzyme family. | 0.923 |
alsS | ilvB-3 | RD1_1674 | RD1_2812 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit. | 0.925 |
alsS | ilvC | RD1_1674 | RD1_1954 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.972 |
alsS | ilvD | RD1_1674 | RD1_0332 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.618 |
alsS | ilvD-2 | RD1_1674 | RD1_3693 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.477 |
alsS | ilvN | RD1_1674 | RD1_2813 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | Acetolactate synthase, small subunit. | 0.987 |
alsS | leuB | RD1_1674 | RD1_0228 | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.946 |
ilvB-2 | RD1_0686 | RD1_2449 | RD1_0686 | Acetolactate synthase; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase, putative; Belongs to the IlvD/Edd family. | 0.456 |
ilvB-2 | alsS | RD1_2449 | RD1_1674 | Acetolactate synthase; Belongs to the TPP enzyme family. | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | 0.923 |
ilvB-2 | ilvB-3 | RD1_2449 | RD1_2812 | Acetolactate synthase; Belongs to the TPP enzyme family. | Acetolactate synthase, large subunit. | 0.926 |