STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acoBThiamine pyrophosphate-dependent dehydrogenase, E1 component (beta subunit, PdhB-like). (326 aa)    
Predicted Functional Partners:
lpd
Dihydrolipoamide dehydrogenase.
 
 0.999
aceF
Branched-chain alpha-keto acid dehydrogenase subunit E2 (lipoate acyltransferase).
 
 0.999
acoA
Thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit (pyruvate dehydrogenase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
sfcA
NAD+-dependent malic enzyme.
  
 
 0.936
lplA
Lipoate-protein ligase A.
  
 
 0.880
fba
Fructose-bisphosphate aldolase.
  
 
 0.870
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.868
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
    
 0.825
rplT
LSU ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
     
 0.599
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
 
  
 0.536
Your Current Organism:
Phytoplasma mali
NCBI taxonomy Id: 37692
Other names: Apple proliferation mycoplasma-like organism, Apple proliferation phytoplasma, C. Phytoplasma mali, Candidatus Phytoplasma mali
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