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fpg protein (Teredinibacter turnerae) - STRING interaction network
"fpg" - formamidopyrimidine-DNA glycosylase in Teredinibacter turnerae
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fpgformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (272 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3’-hydroxyl group of dephosphocoenzyme A to form coenzyme A (202 aa)
 
   
  0.939
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4’- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (162 aa)
   
 
  0.898
mutY
A/G-specific adenine glycosylase (352 aa)
   
 
  0.889
polA
DNA polymerase I (908 aa)
   
   
  0.801
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (441 aa)
   
 
  0.729
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (613 aa)
   
   
  0.725
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (864 aa)
   
 
  0.700
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (315 aa)
     
 
  0.631
dnaE2
DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase (1033 aa)
     
 
  0.628
tatC
Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (255 aa)
   
 
  0.626
Your Current Organism:
Teredinibacter turnerae
NCBI taxonomy Id: 377629
Other names: A. genera incertae sedis, Alteromonadales genera incertae sedis, T. turnerae, T. turnerae T7901, Teredinibacter, Teredinibacter Distel et al. 2002, Teredinibacter turnerae, Teredinibacter turnerae Distel et al. 2002, Teredinibacter turnerae T7901, Teredinibacter turnerae str. T7901, Teredinibacter turnerae strain T7901
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