node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACR11599.1 | gcvP | TERTU_3017 | TERTU_0724 | Hydro-lyase, Fe-S type, tartrate/fumarate family; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.962 |
ACR11599.1 | glyA | TERTU_3017 | TERTU_3707 | Hydro-lyase, Fe-S type, tartrate/fumarate family; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.484 |
ACR13382.1 | ACR14230.1 | TERTU_0759 | TERTU_3576 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.999 |
ACR13382.1 | gcvH | TERTU_0759 | TERTU_0357 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.873 |
ACR13382.1 | gcvP | TERTU_0759 | TERTU_0724 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.940 |
ACR13382.1 | gcvT | TERTU_0759 | TERTU_0356 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.896 |
ACR13382.1 | glyA | TERTU_0759 | TERTU_3707 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.411 |
ACR13382.1 | lpdA | TERTU_0759 | TERTU_2520 | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.873 |
ACR14101.1 | gcvH | TERTU_1992 | TERTU_0357 | Identified by match to protein family HMM PF00155; match to protein family HMM PF00266. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.408 |
ACR14101.1 | gcvP | TERTU_1992 | TERTU_0724 | Identified by match to protein family HMM PF00155; match to protein family HMM PF00266. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.943 |
ACR14101.1 | gcvT | TERTU_1992 | TERTU_0356 | Identified by match to protein family HMM PF00155; match to protein family HMM PF00266. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.537 |
ACR14101.1 | glyA | TERTU_1992 | TERTU_3707 | Identified by match to protein family HMM PF00155; match to protein family HMM PF00266. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.929 |
ACR14101.1 | ltaE | TERTU_1992 | TERTU_3986 | Identified by match to protein family HMM PF00155; match to protein family HMM PF00266. | L-threonine aldolase, low-specificity; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.905 |
ACR14230.1 | ACR13382.1 | TERTU_3576 | TERTU_0759 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.999 |
ACR14230.1 | gcvH | TERTU_3576 | TERTU_0357 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.873 |
ACR14230.1 | gcvP | TERTU_3576 | TERTU_0724 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.940 |
ACR14230.1 | gcvT | TERTU_3576 | TERTU_0356 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.896 |
ACR14230.1 | glyA | TERTU_3576 | TERTU_3707 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.411 |
ACR14230.1 | lpdA | TERTU_3576 | TERTU_2520 | Glutamate synthase [NADPH], large subunit; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.873 |
gcvH | ACR13382.1 | TERTU_0357 | TERTU_0759 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamate synthase [NADH/NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.873 |