node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACR12261.1 | ACR13424.1 | TERTU_2332 | TERTU_4298 | Non-ribosomal polypeptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733. | Alternative name: Type I polyketide synthase; identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801. | 0.988 |
ACR12261.1 | ACS93560.1 | TERTU_2332 | TERTU_2333 | Non-ribosomal polypeptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733. | Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733. | 0.949 |
ACR12261.1 | hemL | TERTU_2332 | TERTU_3069 | Non-ribosomal polypeptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.722 |
ACR12948.1 | hemL | TERTU_3067 | TERTU_3069 | Identified by match to protein family HMM PF08543. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.774 |
ACR12948.1 | thiE | TERTU_3067 | TERTU_3068 | Identified by match to protein family HMM PF08543. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.997 |
ACR13424.1 | ACR12261.1 | TERTU_4298 | TERTU_2332 | Alternative name: Type I polyketide synthase; identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801. | Non-ribosomal polypeptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733. | 0.988 |
ACR13424.1 | ACS93560.1 | TERTU_4298 | TERTU_2333 | Alternative name: Type I polyketide synthase; identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801. | Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733. | 0.990 |
ACR13424.1 | hemL | TERTU_4298 | TERTU_3069 | Alternative name: Type I polyketide synthase; identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.910 |
ACS93560.1 | ACR12261.1 | TERTU_2333 | TERTU_2332 | Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733. | Non-ribosomal polypeptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01720; match to protein family HMM TIGR01733. | 0.949 |
ACS93560.1 | ACR13424.1 | TERTU_2333 | TERTU_4298 | Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733. | Alternative name: Type I polyketide synthase; identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801. | 0.990 |
ACS93560.1 | hemL | TERTU_2333 | TERTU_3069 | Non-ribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.759 |
cobA | cysG | TERTU_2949 | TERTU_1974 | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.961 |
cobA | hemA | TERTU_2949 | TERTU_3845 | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.777 |
cobA | hemB | TERTU_2949 | TERTU_0658 | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. | 0.871 |
cobA | hemC | TERTU_2949 | TERTU_0197 | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
cobA | hemL | TERTU_2949 | TERTU_3069 | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. | 0.738 |
cysG | cobA | TERTU_1974 | TERTU_2949 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469. | 0.961 |
cysG | hemA | TERTU_1974 | TERTU_3845 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.828 |
cysG | hemB | TERTU_1974 | TERTU_0658 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family. | 0.910 |
cysG | hemC | TERTU_1974 | TERTU_0197 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.987 |