STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (639 aa)    
Predicted Functional Partners:
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF01256; match to protein family HMM PF08543; match to protein family HMM TIGR00097.
 
 
 0.995
ACR12948.1
Identified by match to protein family HMM PF08543.
 
 
 0.982
thiG
Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.962
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.946
ACR11253.1
Fusion of MutT/nudix family protein and thiamine monophosphate synthase; Identified by match to protein family HMM PF00293; match to protein family HMM PF02581; match to protein family HMM TIGR00586; Belongs to the Nudix hydrolase family.
  
  
 0.871
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
  
 0.843
ACR12962.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF02597; match to protein family HMM PF05237.
 
  
 0.815
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878; match to protein family HMM TIGR01847.
     
 0.807
ACR13141.1
ThiF domain containing protein; Identified by similarity to SP:P12282; match to protein family HMM PF00899; match to protein family HMM PF05237.
 
  
 0.749
ACR13942.1
Nudix hydroxylase; Identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052.
     
 0.628
Your Current Organism:
Teredinibacter turnerae T7901
NCBI taxonomy Id: 377629
Other names: T. turnerae T7901, Teredinibacter turnerae str. T7901, Teredinibacter turnerae strain T7901
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