STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (355 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
bioA
Protein synonym: 7,8-diamino-pelargonic acid aminotransferase; protein synonym: DAPA aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.997
GAU_3545
Omega-amino acid--pyruvate aminotransferase; Protein synonym: beta-alanine--pyruvate aminotransferase; protein synonym: omega-APT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.984
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
  
 0.934
GAU_1534
biotin--[acetyl-CoA-carboxylase] ligase.
  
 
 0.932
kbl
Putative 2-amino-3-ketobutyrate coenzyme A ligase; Protein synonym: AKB ligase; protein synonym: glycine acetyltransferase.
  
 0.856
thiE/thiD
Thiamine-phosphate pyrophosphorylase/phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.643
rocD
Protein synonym: ornithine--oxo-acid aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.616
argD
Acetylornithine/succinyldiaminopimelate aminotransferase; Bifunctional protein; protein synonym: ACOAT; protein synonym: DapATase; protein synonym: succinyldiaminopimelate transferase.
 
 
  
 0.557
glcD
Glycolate oxidase subunit GlcD.
 
    
 0.494
Your Current Organism:
Gemmatimonas aurantiaca
NCBI taxonomy Id: 379066
Other names: G. aurantiaca T-27, Gemmatimonas aurantiaca DSM 14586, Gemmatimonas aurantiaca JCM 11422, Gemmatimonas aurantiaca NBRC 100505, Gemmatimonas aurantiaca T-27, Gemmatimonas aurantiaca str. T-27, Gemmatimonas aurantiaca strain T-27
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