STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LELG_04389Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family. (432 aa)    
Predicted Functional Partners:
LELG_01531
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 
 0.988
LELG_02174
BPL/LPL catalytic domain-containing protein.
  
 
 0.987
LELG_03551
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 0.987
LELG_03094
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
   
  
 0.616
LELG_05060
40S ribosomal protein S28.
 
 
    0.609
LELG_01411
40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.
 
      0.607
LELG_05558
Cysteine desulfurase, mitochondrial.
   
  
 0.604
LELG_03559
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.601
LELG_05076
Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
     
 0.592
CAF17
Putative transferase CAF17, mitochondrial.
      
 0.591
Your Current Organism:
Lodderomyces elongisporus
NCBI taxonomy Id: 379508
Other names: L. elongisporus NRRL YB-4239, Lodderomyces elongisporus NRRL YB-4239
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