node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHGG_01676 | CHGG_03355 | Q2HDM8 | Q2H8U9 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | Nuclear cap-binding protein subunit 2. | 0.661 |
CHGG_01676 | CHGG_04228 | Q2HDM8 | Q2H1W8 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | Uncharacterized protein. | 0.966 |
CHGG_01676 | CHGG_05567 | Q2HDM8 | Q2H6Z8 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | MIF4G domain-containing protein. | 0.983 |
CHGG_01676 | CHGG_07066 | Q2HDM8 | Q2GY88 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | Helicase ATP-binding domain-containing protein. | 0.570 |
CHGG_01676 | CHGG_08955 | Q2HDM8 | Q2GSU9 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | Tr-type G domain-containing protein. | 0.490 |
CHGG_01676 | CHGG_10460 | Q2HDM8 | Q2GNJ4 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | LsmAD domain-containing protein. | 0.495 |
CHGG_01676 | PAB1 | Q2HDM8 | Q2GSX8 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.975 |
CHGG_01676 | PAN2 | Q2HDM8 | Q2GSV2 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] | 0.601 |
CHGG_01676 | PAN3 | Q2HDM8 | Q2H401 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] | 0.609 |
CHGG_01676 | TIF1 | Q2HDM8 | Q2HFP1 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.971 |
CHGG_03355 | CHGG_01676 | Q2H8U9 | Q2HDM8 | Nuclear cap-binding protein subunit 2. | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | 0.661 |
CHGG_03355 | CHGG_04228 | Q2H8U9 | Q2H1W8 | Nuclear cap-binding protein subunit 2. | Uncharacterized protein. | 0.827 |
CHGG_03355 | CHGG_05567 | Q2H8U9 | Q2H6Z8 | Nuclear cap-binding protein subunit 2. | MIF4G domain-containing protein. | 0.827 |
CHGG_03355 | CHGG_07066 | Q2H8U9 | Q2GY88 | Nuclear cap-binding protein subunit 2. | Helicase ATP-binding domain-containing protein. | 0.884 |
CHGG_03355 | CHGG_10460 | Q2H8U9 | Q2GNJ4 | Nuclear cap-binding protein subunit 2. | LsmAD domain-containing protein. | 0.437 |
CHGG_03355 | PAB1 | Q2H8U9 | Q2GSX8 | Nuclear cap-binding protein subunit 2. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.934 |
CHGG_03355 | TIF1 | Q2H8U9 | Q2HFP1 | Nuclear cap-binding protein subunit 2. | ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.637 |
CHGG_04228 | CHGG_01676 | Q2H1W8 | Q2HDM8 | Uncharacterized protein. | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | 0.966 |
CHGG_04228 | CHGG_03355 | Q2H1W8 | Q2H8U9 | Uncharacterized protein. | Nuclear cap-binding protein subunit 2. | 0.827 |
CHGG_04228 | CHGG_07066 | Q2H1W8 | Q2GY88 | Uncharacterized protein. | Helicase ATP-binding domain-containing protein. | 0.744 |