node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0100 | AHA_0102 | AHA_0100 | AHA_0102 | Hypothetical protein; Identified by Glimmer2; putative. | NAD(P)H-flavin reductase (FMN reductase); Aquacobalamin reductase; NAD(P)H:flavin oxidoreductase; identified by match to protein family HMM PF00175; match to protein family HMM PF00970. | 0.447 |
AHA_0100 | rho | AHA_0100 | AHA_0099 | Hypothetical protein; Identified by Glimmer2; putative. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.472 |
AHA_0100 | ubiD | AHA_0100 | AHA_0101 | Hypothetical protein; Identified by Glimmer2; putative. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.709 |
AHA_0102 | AHA_0100 | AHA_0102 | AHA_0100 | NAD(P)H-flavin reductase (FMN reductase); Aquacobalamin reductase; NAD(P)H:flavin oxidoreductase; identified by match to protein family HMM PF00175; match to protein family HMM PF00970. | Hypothetical protein; Identified by Glimmer2; putative. | 0.447 |
AHA_0102 | ubiD | AHA_0102 | AHA_0101 | NAD(P)H-flavin reductase (FMN reductase); Aquacobalamin reductase; NAD(P)H:flavin oxidoreductase; identified by match to protein family HMM PF00175; match to protein family HMM PF00970. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.682 |
AHA_1717 | ubiA | AHA_1717 | AHA_0181 | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.708 |
AHA_1717 | ubiD | AHA_1717 | AHA_0101 | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.913 |
AHA_1717 | ubiE | AHA_1717 | AHA_0084 | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.485 |
AHA_1717 | ubiX | AHA_1717 | AHA_3548 | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | 3-octaprenyl-4-hydroxybenzoate decarboxylase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.912 |
AHA_2576 | ubiD | AHA_2576 | AHA_0101 | Anaerobic sulfite reductase subunit B; Identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02911. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.433 |
rho | AHA_0100 | AHA_0099 | AHA_0100 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Hypothetical protein; Identified by Glimmer2; putative. | 0.472 |
rho | ubiD | AHA_0099 | AHA_0101 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.436 |
ubiA | AHA_1717 | AHA_0181 | AHA_1717 | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | 0.708 |
ubiA | ubiD | AHA_0181 | AHA_0101 | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | 0.962 |
ubiA | ubiE | AHA_0181 | AHA_0084 | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.511 |
ubiA | ubiX | AHA_0181 | AHA_3548 | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-octaprenyl-4-hydroxybenzoate decarboxylase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.963 |
ubiD | AHA_0100 | AHA_0101 | AHA_0100 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Hypothetical protein; Identified by Glimmer2; putative. | 0.709 |
ubiD | AHA_0102 | AHA_0101 | AHA_0102 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | NAD(P)H-flavin reductase (FMN reductase); Aquacobalamin reductase; NAD(P)H:flavin oxidoreductase; identified by match to protein family HMM PF00175; match to protein family HMM PF00970. | 0.682 |
ubiD | AHA_1717 | AHA_0101 | AHA_1717 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Protein VisC; Identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988. | 0.913 |
ubiD | AHA_2576 | AHA_0101 | AHA_2576 | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis. | Anaerobic sulfite reductase subunit B; Identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02911. | 0.433 |