node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0132 | tusA | AHA_0132 | AHA_0133 | Endoribonuclease L-PSP; Identified by match to protein family HMM PF01042. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.725 |
AHA_1675 | AHA_3296 | AHA_1675 | AHA_3296 | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Identified by match to protein family HMM PF02635. | 0.615 |
AHA_1675 | AHA_4024 | AHA_1675 | AHA_4024 | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Intracellular sulfur oxidation protein DsrE; Identified by match to protein family HMM PF02635; match to protein family HMM TIGR03012. | 0.963 |
AHA_1675 | iscS | AHA_1675 | AHA_1747 | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.978 |
AHA_1675 | thiI | AHA_1675 | AHA_1695 | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.438 |
AHA_1675 | tusA | AHA_1675 | AHA_0133 | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.900 |
AHA_3296 | AHA_1675 | AHA_3296 | AHA_1675 | Identified by match to protein family HMM PF02635. | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.615 |
AHA_3296 | tusA | AHA_3296 | AHA_0133 | Identified by match to protein family HMM PF02635. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.615 |
AHA_4024 | AHA_1675 | AHA_4024 | AHA_1675 | Intracellular sulfur oxidation protein DsrE; Identified by match to protein family HMM PF02635; match to protein family HMM TIGR03012. | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.963 |
AHA_4024 | tusA | AHA_4024 | AHA_0133 | Intracellular sulfur oxidation protein DsrE; Identified by match to protein family HMM PF02635; match to protein family HMM TIGR03012. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.974 |
dusC | thiI | AHA_2208 | AHA_1695 | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.621 |
dusC | trmU | AHA_2208 | AHA_1415 | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.579 |
dusC | tusA | AHA_2208 | AHA_0133 | tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.606 |
iscS | AHA_1675 | AHA_1747 | AHA_1675 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Conserved hypothetical protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. | 0.978 |
iscS | thiI | AHA_1747 | AHA_1695 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.986 |
iscS | trmU | AHA_1747 | AHA_1415 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.580 |
iscS | tusA | AHA_1747 | AHA_0133 | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.981 |
moaD | thiI | AHA_1593 | AHA_1695 | Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597; match to protein family HMM TIGR01682. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.417 |
moaD | tusA | AHA_1593 | AHA_0133 | Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597; match to protein family HMM TIGR01682. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.719 |
queE | tusA | AHA_1817 | AHA_0133 | Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family. | 0.663 |