node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0039 | AHA_0819 | AHA_0039 | AHA_0819 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.920 |
AHA_0039 | AHA_2412 | AHA_0039 | AHA_2412 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate cyclase; Identified by match to protein family HMM PF01928; match to protein family HMM TIGR00318. | 0.900 |
AHA_0039 | RelA | AHA_0039 | AHA_0818 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((p)ppGpp synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.917 |
AHA_0039 | cyaA | AHA_0039 | AHA_0470 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Adenylate cyclase, class I; Identified by similarity to SP:P00936; match to protein family HMM PF01295; Belongs to the adenylyl cyclase class-1 family. | 0.901 |
AHA_0039 | moaA | AHA_0039 | AHA_1583 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.804 |
AHA_0039 | ndk | AHA_0039 | AHA_1755 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
AHA_0039 | nrdD | AHA_0039 | AHA_1231 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF01228; match to protein family HMM PF03477; match to protein family HMM TIGR02487. | 0.900 |
AHA_0039 | pyk-2 | AHA_0039 | AHA_1349 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.915 |
AHA_0039 | pyk-3 | AHA_0039 | AHA_3052 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.913 |
AHA_0819 | AHA_0039 | AHA_0819 | AHA_0039 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.920 |
AHA_0819 | AHA_2412 | AHA_0819 | AHA_2412 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate cyclase; Identified by match to protein family HMM PF01928; match to protein family HMM TIGR00318. | 0.900 |
AHA_0819 | RelA | AHA_0819 | AHA_0818 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((p)ppGpp synthetase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.968 |
AHA_0819 | cpdA | AHA_0819 | AHA_3763 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.919 |
AHA_0819 | cyaA | AHA_0819 | AHA_0470 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate cyclase, class I; Identified by similarity to SP:P00936; match to protein family HMM PF01295; Belongs to the adenylyl cyclase class-1 family. | 0.900 |
AHA_0819 | moaA | AHA_0819 | AHA_1583 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.807 |
AHA_0819 | ndk | AHA_0819 | AHA_1755 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
AHA_0819 | nrdD | AHA_0819 | AHA_1231 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Anaerobic ribonucleoside-triphosphate reductase; Identified by match to protein family HMM PF01228; match to protein family HMM PF03477; match to protein family HMM TIGR02487. | 0.900 |
AHA_0819 | pyk-2 | AHA_0819 | AHA_1349 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.900 |
AHA_0819 | pyk-3 | AHA_0819 | AHA_3052 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.900 |
AHA_2412 | AHA_0039 | AHA_2412 | AHA_0039 | Adenylate cyclase; Identified by match to protein family HMM PF01928; match to protein family HMM TIGR00318. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase ((ppGpp)ase); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |