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hscB protein (Aeromonas hydrophila ATCC7966) - STRING interaction network
"hscB" - Co-chaperone protein HscB homolog in Aeromonas hydrophila ATCC7966
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
hscBCo-chaperone protein HscB homolog; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (172 aa)    
Predicted Functional Partners:
iscU
Iron-sulfur cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters (127 aa)
 
 
  0.997
hscA
Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB (615 aa)
 
  0.994
fdx
Ferredoxin, 2Fe-2S type, ISC system; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 (112 aa)
 
 
  0.992
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily (404 aa)
 
 
  0.975
dnaK
Chaperone protein DnaK; Acts as a chaperone (642 aa)
 
  0.972
iscR
HTH-type transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins (167 aa)
   
 
  0.934
iscA
Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system (107 aa)
 
 
  0.924
cyaY
Protein CyaY; Identified by match to protein family HMM PF01491; Belongs to the frataxin family (104 aa)
   
   
  0.888
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG (134 aa)
 
 
  0.654
gntY
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins (192 aa)
   
 
  0.637
Your Current Organism:
Aeromonas hydrophila ATCC7966
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila ATCC7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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