STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGtp-binding protein enga; GTPase that plays an essential role in the late steps of ribosome biogenesis (499 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017; Belongs to the cytidylate kinase family. Type 1 subfamily
  
 0.940
truB
Trna pseudouridine synthase b; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs
 
  
 0.895
AHA_2917
Ribosomal large subunit pseudouridine synthase b; Belongs to the pseudouridine synthase RsuA family
 
  
 0.884
rplT
Ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
  
 
 
 0.860
rplO
Ribosomal protein l15; Binds to the 23S rRNA
  
 
 0.852
obg
Gtp-binding protein obg/cgta; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
 
  
 0.850
hisS
Histidyl-trna synthetase; Histidine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442
 
  
 0.801
rplA
Ribosomal protein l1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
  
 
 
 0.795
engB
Gtp-binding protein yiha; Necessary for normal cell division and for the maintenance of normal septation
 
  
 0.787
mraW
S-adenosyl-methyltransferase mraw; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
 
  
 0.784
Your Current Organism:
Aeromonas hydrophila ATCC7966
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
Server load: low (12%) [HD]