STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnaATyrosine phenol-lyase; Identified by match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. (461 aa)    
Predicted Functional Partners:
AHA_1127
4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme; Identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383.
    
   0.669
AHA_1316
Identified by match to protein family HMM PF01575.
      
 0.570
AHA_3285
TtrA; Identified by match to protein family HMM PF01568; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
      
 0.530
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
      
 0.525
AHA_0123
Low affinity tryptophan permease; Identified by match to protein family HMM PF03222; match to protein family HMM TIGR00837.
  
  
 0.480
AHA_0465
Proteinase inhibitor; Identified by match to protein family HMM PF03692.
    
   0.444
hchA
Chaperone protein HchA; Identified by match to protein family HMM PF01965.
    
   0.444
luxS
S-Ribosylhomocysteinase (LuxS); Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.442
MotB
Sodium-driven polar flagellar protein; Identified by match to protein family HMM PF00691.
      
 0.442
prc
C-terminal processing peptidase; Identified by similarity to SP:P23865; match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; Belongs to the peptidase S41A family.
      
 0.441
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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