STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minCProbable septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (240 aa)    
Predicted Functional Partners:
minD
Identified by match to protein family HMM PF01656; match to protein family HMM TIGR01968; Belongs to the ParA family
 
 0.999
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
 
  
 0.968
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
    
 
 0.768
AHA_2135
YcgL domain-containing protein AHA_2135; Identified by match to protein family HMM PF05166
       0.630
AHA_2136
Membrane-bound lytic murein transglycosylase B; Identified by match to protein family HMM TIGR02283
       0.616
mreB
Rod shape-determining protein MreB; Identified by match to protein family HMM PF06723; match to protein family HMM TIGR00904
     
 0.515
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
     
 0.461
AHA_2131
annotation not available
       0.443
AHA_1865
FtsK/SpoIIIE family protein; Identified by similarity to SP:P46889; match to protein family HMM PF01580
     
 0.426
ftsE
Cell division ATP-binding protein FtsE; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR02673
      
 0.424
Your Current Organism:
Aeromonas hydrophila ATCC7966
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila ATCC7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
Server load: low (7%) [HD]