node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_2486 | add-2 | AHA_2486 | AHA_2653 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.576 |
AHA_2486 | adk | AHA_2486 | AHA_2489 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.416 |
AHA_2486 | apt | AHA_2486 | AHA_2210 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.931 |
AHA_2486 | gmk | AHA_2486 | AHA_0041 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.908 |
AHA_2486 | gpt | AHA_2486 | AHA_3424 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.940 |
AHA_2486 | guaA | AHA_2486 | AHA_1990 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.934 |
AHA_2486 | guaC | AHA_2486 | AHA_3225 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.904 |
AHA_2486 | hpt | AHA_2486 | AHA_3546 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.907 |
AHA_2486 | purH | AHA_2486 | AHA_0841 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.911 |
add-2 | AHA_2486 | AHA_2653 | AHA_2486 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | 0.576 |
add-2 | apt | AHA_2653 | AHA_2210 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.942 |
add-2 | gpt | AHA_2653 | AHA_3424 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.435 |
add-2 | guaA | AHA_2653 | AHA_1990 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.564 |
add-2 | hpt | AHA_2653 | AHA_3546 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.916 |
adk | AHA_2486 | AHA_2489 | AHA_2486 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | 0.416 |
adk | apt | AHA_2489 | AHA_2210 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.936 |
adk | gmk | AHA_2489 | AHA_0041 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.806 |
adk | guaA | AHA_2489 | AHA_1990 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.531 |
adk | hpt | AHA_2489 | AHA_3546 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.901 |
adk | purB | AHA_2489 | AHA_1413 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.957 |