node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_2486 | apt | AHA_2486 | AHA_2210 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.931 |
AHA_2486 | deoD-1 | AHA_2486 | AHA_3010 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.900 |
AHA_2486 | gmk | AHA_2486 | AHA_0041 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.908 |
AHA_2486 | gpt | AHA_2486 | AHA_3424 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.940 |
AHA_2486 | guaA | AHA_2486 | AHA_1990 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.934 |
AHA_2486 | guaB | AHA_2486 | AHA_1989 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.914 |
AHA_2486 | guaC | AHA_2486 | AHA_3225 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.904 |
AHA_2486 | hpt | AHA_2486 | AHA_3546 | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.907 |
apt | AHA_2486 | AHA_2210 | AHA_2486 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | 0.931 |
apt | deoD-1 | AHA_2210 | AHA_3010 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.912 |
apt | gmk | AHA_2210 | AHA_0041 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
apt | gpt | AHA_2210 | AHA_3424 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.969 |
apt | guaA | AHA_2210 | AHA_1990 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.986 |
apt | guaB | AHA_2210 | AHA_1989 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.550 |
apt | guaC | AHA_2210 | AHA_3225 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.970 |
apt | hpt | AHA_2210 | AHA_3546 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.969 |
apt | xapA | AHA_2210 | AHA_0958 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.675 |
deoD-1 | AHA_2486 | AHA_3010 | AHA_2486 | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | Inosine-guanosine kinase; Identified by match to protein family HMM PF00294. | 0.900 |
deoD-1 | apt | AHA_3010 | AHA_2210 | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.912 |
deoD-1 | gpt | AHA_3010 | AHA_3424 | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.911 |