node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0790 | AHA_1404 | AHA_0790 | AHA_1404 | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Putative glutaredoxin homolog; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.502 |
AHA_0790 | cyaY | AHA_0790 | AHA_0472 | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.411 |
AHA_0790 | erpA | AHA_0790 | AHA_3517 | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.619 |
AHA_0790 | gntY | AHA_0790 | AHA_0297 | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.698 |
AHA_0790 | iscS | AHA_0790 | AHA_1747 | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.451 |
AHA_1404 | AHA_0790 | AHA_1404 | AHA_0790 | Putative glutaredoxin homolog; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | 0.502 |
AHA_1404 | erpA | AHA_1404 | AHA_3517 | Putative glutaredoxin homolog; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.616 |
AHA_1404 | gntY | AHA_1404 | AHA_0297 | Putative glutaredoxin homolog; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | Protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.804 |
AHA_1404 | iscU | AHA_1404 | AHA_1748 | Putative glutaredoxin homolog; Identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365; Belongs to the glutaredoxin family. Monothiol subfamily. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.419 |
AHA_3209 | cyaY | AHA_3209 | AHA_0472 | Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.643 |
AHA_3209 | erpA | AHA_3209 | AHA_3517 | Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.548 |
AHA_3209 | gntY | AHA_3209 | AHA_0297 | Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.834 |
AHA_3209 | petA | AHA_3209 | AHA_3903 | Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.886 |
AHA_3518 | erpA | AHA_3518 | AHA_3517 | Conserved hypothetical protein. | HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.704 |
cyaY | AHA_0790 | AHA_0472 | AHA_0790 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Chain A, Ygfz Protein; Identified by match to protein family HMM PF01571; Belongs to the GcvT family. | 0.411 |
cyaY | AHA_3209 | AHA_0472 | AHA_3209 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Fumarate reductase iron-sulfur protein; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.643 |
cyaY | erpA | AHA_0472 | AHA_3517 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | HesB family protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.690 |
cyaY | gntY | AHA_0472 | AHA_0297 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.670 |
cyaY | hscB | AHA_0472 | AHA_1750 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.827 |
cyaY | iscS | AHA_0472 | AHA_1747 | Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.985 |