node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACG56813.1 | ACG57570.1 | HY04AAS1_0121 | HY04AAS1_0883 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | PFAM: 3-dehydroquinate synthase; KEGG: sul:SYO3AOP1_0392 3-dehydroquinate synthase; Belongs to the archaeal-type DHQ synthase family. | 0.982 |
ACG56813.1 | aroA | HY04AAS1_0121 | HY04AAS1_0983 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.942 |
ACG56813.1 | aroC | HY04AAS1_0121 | HY04AAS1_0221 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.986 |
ACG56813.1 | aroD | HY04AAS1_0121 | HY04AAS1_0220 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.568 |
ACG56813.1 | aroE | HY04AAS1_0121 | HY04AAS1_1184 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.703 |
ACG56813.1 | aroK | HY04AAS1_0121 | HY04AAS1_1039 | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.724 |
ACG56914.1 | aroC | HY04AAS1_0222 | HY04AAS1_0221 | KEGG: bbt:BBta_1404 hypothetical protein. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.405 |
ACG56914.1 | aroD | HY04AAS1_0222 | HY04AAS1_0220 | KEGG: bbt:BBta_1404 hypothetical protein. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.405 |
ACG57570.1 | ACG56813.1 | HY04AAS1_0883 | HY04AAS1_0121 | PFAM: 3-dehydroquinate synthase; KEGG: sul:SYO3AOP1_0392 3-dehydroquinate synthase; Belongs to the archaeal-type DHQ synthase family. | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.982 |
ACG57570.1 | aroD | HY04AAS1_0883 | HY04AAS1_0220 | PFAM: 3-dehydroquinate synthase; KEGG: sul:SYO3AOP1_0392 3-dehydroquinate synthase; Belongs to the archaeal-type DHQ synthase family. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.918 |
ACG57570.1 | aroE | HY04AAS1_0883 | HY04AAS1_1184 | PFAM: 3-dehydroquinate synthase; KEGG: sul:SYO3AOP1_0392 3-dehydroquinate synthase; Belongs to the archaeal-type DHQ synthase family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.401 |
aroA | ACG56813.1 | HY04AAS1_0983 | HY04AAS1_0121 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.942 |
aroA | aroC | HY04AAS1_0983 | HY04AAS1_0221 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
aroA | aroD | HY04AAS1_0983 | HY04AAS1_0220 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.421 |
aroA | aroE | HY04AAS1_0983 | HY04AAS1_1184 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.993 |
aroA | aroK | HY04AAS1_0983 | HY04AAS1_1039 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.986 |
aroC | ACG56813.1 | HY04AAS1_0221 | HY04AAS1_0121 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: aae:aq_951 chorismate mutase/prephenate dehydratase. | 0.986 |
aroC | ACG56914.1 | HY04AAS1_0221 | HY04AAS1_0222 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | KEGG: bbt:BBta_1404 hypothetical protein. | 0.405 |
aroC | aroA | HY04AAS1_0221 | HY04AAS1_0983 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.998 |
aroC | aroD | HY04AAS1_0221 | HY04AAS1_0220 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.895 |