node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACG56728.1 | ACG57459.1 | HY04AAS1_0036 | HY04AAS1_0772 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | 0.986 |
ACG56728.1 | ACG57713.1 | HY04AAS1_0036 | HY04AAS1_1027 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein; KEGG: mse:Msed_0839 DNA topoisomerase, type IA, central domain protein. | 0.775 |
ACG56728.1 | ACG57774.1 | HY04AAS1_0036 | HY04AAS1_1088 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
ACG56728.1 | ACG58139.1 | HY04AAS1_0036 | HY04AAS1_1455 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | PFAM: UvrD/REP helicase; KEGG: aae:aq_793 ATP-dependent DNA helicase REP. | 0.725 |
ACG56728.1 | acpP | HY04AAS1_0036 | HY04AAS1_0510 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.663 |
ACG56728.1 | recA | HY04AAS1_0036 | HY04AAS1_1372 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.955 |
ACG56728.1 | sbcD | HY04AAS1_0036 | HY04AAS1_1090 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.997 |
ACG57459.1 | ACG56728.1 | HY04AAS1_0772 | HY04AAS1_0036 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain. | 0.986 |
ACG57459.1 | ACG57468.1 | HY04AAS1_0772 | HY04AAS1_0781 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | SMC domain protein; May be involved in recombinational repair of damaged DNA. | 0.590 |
ACG57459.1 | ACG57713.1 | HY04AAS1_0772 | HY04AAS1_1027 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein; KEGG: mse:Msed_0839 DNA topoisomerase, type IA, central domain protein. | 0.884 |
ACG57459.1 | ACG57774.1 | HY04AAS1_0772 | HY04AAS1_1088 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.637 |
ACG57459.1 | ACG58139.1 | HY04AAS1_0772 | HY04AAS1_1455 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | PFAM: UvrD/REP helicase; KEGG: aae:aq_793 ATP-dependent DNA helicase REP. | 0.518 |
ACG57459.1 | acpP | HY04AAS1_0772 | HY04AAS1_0510 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.617 |
ACG57459.1 | recA | HY04AAS1_0772 | HY04AAS1_1372 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.846 |
ACG57459.1 | sbcD | HY04AAS1_0772 | HY04AAS1_1090 | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
ACG57468.1 | ACG57459.1 | HY04AAS1_0781 | HY04AAS1_0772 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC. | 0.590 |
ACG57468.1 | ACG57713.1 | HY04AAS1_0781 | HY04AAS1_1027 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein; KEGG: mse:Msed_0839 DNA topoisomerase, type IA, central domain protein. | 0.480 |
ACG57468.1 | ACG58139.1 | HY04AAS1_0781 | HY04AAS1_1455 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | PFAM: UvrD/REP helicase; KEGG: aae:aq_793 ATP-dependent DNA helicase REP. | 0.402 |
ACG57468.1 | radA | HY04AAS1_0781 | HY04AAS1_0963 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.427 |
ACG57468.1 | recA | HY04AAS1_0781 | HY04AAS1_1372 | SMC domain protein; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.829 |