node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OBQ57908.1 | OBQ57945.1 | A8146_22980 | A8146_23190 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
OBQ57908.1 | OBQ59387.1 | A8146_22980 | A8146_21130 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.596 |
OBQ57908.1 | OBQ63260.1 | A8146_22980 | A8146_12320 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridoxal-5'-phosphate-dependent protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
OBQ57908.1 | OBQ74765.1 | A8146_22980 | A8146_03215 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.951 |
OBQ57908.1 | ilvA | A8146_22980 | A8146_17315 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.924 |
OBQ57908.1 | ilvC | A8146_22980 | A8146_03320 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.517 |
OBQ57908.1 | ilvD | A8146_22980 | A8146_04500 | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.402 |
OBQ57945.1 | OBQ57908.1 | A8146_23190 | A8146_22980 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
OBQ57945.1 | OBQ58006.1 | A8146_23190 | A8146_23195 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
OBQ57945.1 | OBQ58615.1 | A8146_23190 | A8146_22045 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Class II aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
OBQ57945.1 | OBQ59387.1 | A8146_23190 | A8146_21130 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.579 |
OBQ57945.1 | OBQ63260.1 | A8146_23190 | A8146_12320 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyridoxal-5'-phosphate-dependent protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
OBQ57945.1 | OBQ74370.1 | A8146_23190 | A8146_00950 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydroxyectoine utilization dehydratase EutB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
OBQ57945.1 | OBQ74765.1 | A8146_23190 | A8146_03215 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |
OBQ57945.1 | ilvA | A8146_23190 | A8146_17315 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.606 |
OBQ57945.1 | ilvC | A8146_23190 | A8146_03320 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.808 |
OBQ57945.1 | ilvD | A8146_23190 | A8146_04500 | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.560 |
OBQ58006.1 | OBQ57945.1 | A8146_23195 | A8146_23190 | Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.772 |
OBQ58615.1 | OBQ57945.1 | A8146_22045 | A8146_23190 | Class II aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.600 |
OBQ59387.1 | OBQ57908.1 | A8146_21130 | A8146_22980 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.596 |